Chemistry
Thousand Protein Multiplexed Mass Spectrometry Assay for Biomarker Discovery
Understanding fundamental processes in Dielectric Barrier Discharge Devices used in air quality improvement.
Air Phaser is a proprietary product produced by Air Phaser Environmental and designed to oxidize and/or reduce air-borne pollutants that need to be transformed to environmentally benign forms. The Air Phaser uses electrical discharges to destroy and break down the VOC’s present in the contaminated air. Although, the technology is effective for many VOC’s, some classes of compounds, specifically aromatic species, are not degraded enough to completely eliminate odor or potential adverse health impacts.
CO2-Triggered Separation Technologies for the Recycling of Industrial Chemical Waste Streams
Synthesis of ligand-lipid conjugates to enhance intracellular delivery of siRNA-lipid nanoparticles to non-liver tissues in vivo
Development of new analytical methods for Nutraceutical and Functional food industry
A series of rapid and cost effective analytical methods will be developed to enable routine screening of feedstock material and products. These techniques include sampling with lasers so that the need for digestion with highly corrisive acids is effectively eliminated. These techniques will have less waste and use less hazardous materials than traditional methods and this will reduce the environmental impact of critical analytical testing. Developing these technologies will ensure that Natural Factors continues to be an industrial leader in quality assurance and cont
Gas Phase and Surface Chemical Consequences of Dielectric Barrier Discharge Plasmas
The proposed research will work to characterize plasmas of the type that form where the charging roll contacts the photoreceptor in a typical xerographic printer. Laboratory experiments will form discharges under ambient atmospheric conditions and at the high-vacuum exit of a dielectric-barrier-discharge pulsed molecular beam. Spectroscopic measurements will record fluorescence emission signatures of plasmas under these conditions, and time-of-flight mass spectrometry will monitor the presence of reactive intermediates.
Electrochemically gated nanoparticle film field effect transistor: fundamental charge transport studies (part 1) and energy storage applications (part 2)
There have been tremendous advances over the past few decades relating to the synthesis and characterization of nanostructures. People have fabricated various types of nano-scale particles, rods, tubes, shells, core-shells, etc and ofcourse synthesis of nano-scale molecules has been a goal of organic and inorganic chemistry for a long time.
Structure and Function of a Ribonucleoprotein Particle
The Kothe research group studies the structure and function of small ribonucleoproteins which are involved in ribosome biogenesis, in particular in modification of ribosomal RNA, with the aim of better understanding how the cell assembles large RNAprotein complexes such as the ribosome.
Structure and Function of novel Direct Antimicrobial and Immunomodulatory Peptides
With the advent of antibiotic resistance, it has become increasingly important to develop alternatives to currently used antibiotics. In our laboratory, we have investigated the structure and function of a number of potentially interesting drug candidates. In the proposed project, we will design and develop a new generation of peptides derived from the two peptides mentioned above. The aim will be to find candidate peptides which display immune regulatory activity and direct antimicrobial activity.
Optimal design of experiments in geological carbon storage
The project’s aims are to conduct research on geological carbon storage from the perspective of dynamic analysis and process systems engineering, looking in particular at the dynamics between the wellhead and the CO2 storage reservoir. The main objective is to achieve closed loop operation and management of the reservoir with respect to CO2 sequestration and storage, along with enhanced oil recovery in cases where the reservoir is not fully depleted. The main thrust areas of the project are described below.


