Freeze-drying of antibiotic vials: monitoring and optimizing process trajectories on an industrial scale

There has been an increased use of freeze-drying in the pharmaceutical industry over the past few decades. This step converts a liquid product into a solid one without compromising its integrity, thus prolonging its shelf life. The monitoring and optimization of this process is commonly done by trial-and-error, leading to product quality control issues. Therefore, the implementation of new monitoring tools in this process could allow a better understanding and control.

Tumor engineering of biomaterial based cancer models for drug screening

The intern will use the company’s proprietary biomaterials to create tumors using cancer cells. These tumors can be used as an alternative to animal testing for cancer drugs. These cancer models will cost a fraction of the cost of animal models and can be tested using existing pharmaceutical techniques and equipment. The intern will develop a process to create tumors, then test existing drugs on the model to see how it compares to human and animal testing results.

Algae Wastewater Treatment Rosebud Pilot

Symbiotic EnviroTek Inc, in collaboration with the University of Calgary is undertaking a research project that will pilot and validate the efficacy and robustness of algae as a wastewater treatment technology and demonstrate a new business model for municipal wastewater infrastructure. The project provides a unique opportunity to optimize system performance in a pilot scale commercial environment, on site in the community to be served by the technology.

Development of Advanced In-Situ Recovery Technologies for Oil San

In-situ recovery methods for oils sands are applied to reservoirs containing bitumen that are too deep for mining. To date there has been only one commercially viable in-situ recovery method, Steam-Assisted Gravity Drainage (SAGD), involving high pressure steam injection and bitumen production using horizontal well pairs located near the base of oil sands formations. While SAGD has enabled conversion of significant resources to reserves (about 170 billion barrels), SAGD has many economic and environmental limitations.

Chemical foaming of glass fiber reinforced recycled PET (rPET) and the injection molding performance of the foamable compound

Plastic wastes are a burden to municipal waste managements and have adverse environmental effects. But the daily increase in production of packaging materials and plastic parts make their formation inevitable. Recycling is a wise way of dealing with plastic waste problem as it has both monetary and environmental benefits. The wastes are collected cleaned and reprocessed to make new products. These products if engineered will provide the same performance at much lower cost of production and lower raw materials and natural resources consumption.

Graphene-Oxide Strengthened Separator to Suppress Zinc Dendrites

In this research project, the separator of rechargeable hybrid aqueous batteries (REHABs) is mechanically strengthened with graphene oxide derivatives. ReHABs comprise of a lithium intercalation cathode, zinc anode and an aqueous electrolyte. One of the problems with current ReHABs is the zinc dendritic growth and propagation from the anode, which significantly reduces its operating lifetime. After cycles of charge/discharge, these dendrites grow and propagate through the separator and eventually reach the cathode, thus shortening the battery.

Versatile applications of a safe and efficient peptide in gene/drug delivery - Year Two

Gene therapy is one of the most attractive new therapeutic strategies in the treatment of multiple diseases. However, to apply gene therapy in clinic, an efficient and safe delivery system must be developed to transport these therapeutic reagents to target organs. The existing gene carriers suffer from either high cytotoxicity or immunogenicity problems, which will cause severe side effects when used in human. The new peptide based delivery system we developed demonstrated better performance and lower toxicity than the commercialized product on market.

Structural colors on polymers by femtosecond laser irradiation

Most colors in nature are due to the presence of pigments or dyes. Artificial colors on different materials are produced by incorporating dyes in them. However, the brightest colors in nature, e.g. the colors of butterfly wings and peacock feathers, are generated because of the micro/nano-features on their surface. Unlike the added dyes or pigments in a material, the colors produced by surface features, also called structural colors, do not fade with sunshine and this colors are non-toxic. Laser irradiation can create structural colors on metals by an easy one-step process.

Statistical analysis and interpretation of metabolite profiling results

Data analysis and interpretation is a critical step in metabolomics. In metabolomics studies, large amounts of data must be evaluated by appropriate analytical tools in order to transform data into knowledge. Chenomx Inc. is a company that provides metabolomics research software and services. Its flagship software product Chenomx NMR Suite is an integrated set of tools for identifying and quantifying metabolites in Nuclear magnetic resonance (NMR) spectra.

Evaluation of adsorbents’ properties and optimization of adsorption based processes for gas separations

The objective of this project is, firstly, to evaluate the performance of various adsorbents using various techniques for gas separation and purification applications of commercial interest; and secondly, to optimize and modify the current PSA setup at Xebec Ads. Company. The proposed project will examine various adsorbents provided by Xebec Adsorption Inc. to determine their adsorption capacity, kinetics, selectivity, at different operating conditions.

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