Intertidal dynamics of First Nations’ clam beaches along a proposed liquefied natural gas (LNG) supertanker route

Proposed liquefied natural gas (LNG) developments in the traditional territory of the Kitsumkalum First Nations may have negative consequences for the productivity of local clam beaches resulting in decreased food security for coastal communities. This project will elucidate previously unknown community dynamics and environmental characteristics in clam beaches threatened by approved developments. This will increase comprehension of intertidal and soft sediment ecosystems, while also creating a baseline of environmental and biological conditions prior to LNG development.

SRRM4 protein purification and antibody production

The SRRM4 gene has been recently identified as a key protein responsible for a subtype of highly aggressive prostate cancers, called neuroendocrine prostate cancer (NEPC). Detection of SRRM4 protein in patient tumor biopsies is therefore important to predict and diagnose NEPC, so that early and more effective therapeutic means can be in place. Unfortunately, there is no SRRM4 antibody currently available that can be used for pathological analyses. This project will join force of academic and industrial expertise to develop a SRRM4 antibody that can be used in clinic for NEPC diagnosis.

Synthesis of Carbohydrate Derivatives for the Improvement of Red Blood Cell Storage

Most red blood cells (RBCs) are stored from 1-6 °C in an additive solution of saline, adenine, glucose, and mannitol for up to 42 days. Cryopreservation of RBCs at -80 ºC in 40% glycerol can prolong their shelf life to at least ten years; however, the process to remove glycerol prior to transfusion is time-consuming and precludes the use of cryopreserved RBCs in emergency situations. The proposed research aims to develop non-toxic carbohydrate derivatives to improve the quality of hypothermically-stored RBCs and facilitate the use of cryopreserved RBCs.

Fine-scale habitat use by juvenile Chinook Salmon in the Salish Sea

Juvenile Pacific Salmon survival in the Salish Sea has declined dramatically since the 1980s. Our work is part of the Salish Sea Marine Survival Project (SSMSP), an initiative which seeks to understand this decline. We have been developing an economical, small vessel-based method to study how juvenile Chinook Salmon use their habitat in more detail than was previously possible. We are also developing methods to identify high quality juvenile salmon habitat using freely available satellite images.

Tissue Microstructure of Surgical Specimens depicted with Optical Coherence Tomography

Perimeter Medical Imaging (PMI) has developed an investigational imaging device to aid in achieving clear margins during surgical oncology procedures. This project will employ PMI’s device to image multiple types of human tissues, which have been previously removed during elective or medical procedures. This study will correlate the images obtained using PMI’s device with the true microscopic structure of the tissue, as confirmed by a pathologist.

Developing an On-field Test for Determining Recreational Water Quality

Recreational water sources are important commercial resources and activity hubs. Unfortunately, any public water source is prone to bacterial and viral contamination, which is a major concern for public health agencies. InnovoGENE Biosciences has a developed a simple test that can quickly determine the level of pathogens. Although this method has been rigorously tested in a laboratory, this test is unproven on the field. The intern has a significant understanding of the technology and is most suited to validate the assay and is capable of optimizing the assay for field use.

Material environments as metaphors: enhancing the well-being of people with dementia

The living environments have been increasingly considered as significant to the well-being of people with dementia in both research and practice. Addressing this, practitioners, including developers, operators, and architects who are in charge of the environmental creation of dementia care facilities, need to know the specific requirements of people with dementia, in order to apply this knowledge to their practical works.

Optical Tissue Imaging DICOM/PACS Integration

The aim of this project is to research and develop a new DICOM modality for the optical coherence tomography images obtained by Perimeter’s Optical Tissue Imaging (OTISTM) device. Following the creation of a suitable modality, a novel solution for transfer to and integration with the PACS servers utilized by current Perimeter customers will also be developed. The device currently allows for local storage and review of obtained data, with images only ever transferred onto different servers by Perimeter staff.

Multi-biomarker test for the management of acute cardiac transplant rejection

The high incidence of acute organ rejection following heart transplantation poses major problems for patients, clinicians, and the healthcare system. A major clinical challenge in this regard arises from the difficulty of accurately

Refinement of a Bioelectric Sensor to achieve real-time quantification of BOD

The necessity of cost-efficient and reliable wastewater treatment processes has increased in order to meet more stringent levels of environmental regulations, increased system reliability requirements and tightening operational budgets. To aid in meeting these operational goals, a strong market for low-cost, high-fidelity sensor technology that can relay real-time information to system operators on all aspects of wastewater treatment system performance has developed.