Highly Sensitive Magnetometer

This internship with Photon Control, a Vancouver-based engineering design, development, and manufacturing company is the first phase of a project to design a highly sensitive magnetometer that will act as a non-invasive interface of a human brain to a machine or computer though many other commercial applications of this device are also anticipated. Electrochemical activity in the brain can be interpreted as a “signal” which in turn can be manipulated by a computer to derive information related to thoughts or intentions.

Prediction of Complex Molecule Structures with HDX Mass Spectrometry-guided Molecular Dynamics Simulations Part II – Generalization and Parametrization

Hydrogen/deuterium exchange mass spectrometry (HDX-MS) is a powerful emerging experimental technique which provides important information about the solvent exposed area of complex molecular systems that is not readily available through existing technologies. HDX-MS can be applied to the specific cases of small molecules binding to protein systems, which is very important for the understanding, and new design, of therapeutic compounds, including chemotherapeutic cancer drugs.

Analysis and Classification of Data from 3D Morpho-Functional Assessments

The digital and bio-mechanical analysis of human motion is an attractive research field as it helps one understand and interpret pathologies affecting the body’s articular components. The goal of this project is to develop data analysis and automatic classification methods to differentiate between data from asymptomatic and pathological individuals. The data will be drawn from 3D morpho-functional assessments. Developed methods could eventually be considered for the creation of decision support and pathology diagnosis tools.

Comparison of Different Middle Ear Prostheses in Conducting Mechanical Vibrations for Hearing Reconstruction

Currently, surgeons often reconstruct the middle ear to restore hearing with artificial prostheses that reconnect the middle ear bones that have been destroyed. This process is unpredictable and these prostheses are available in hundreds of different forms from many companies. The supervisor of this project runs one of the foremost laboratories in the world in exploring the vibration transmission properties of prostheses.

Kinematics Modelling and Trajectory Design for Arm and Shoulder Physical Therapies Performed by Rehabilitation Robots

This project involves studying the kinematics of the human body during physical therapies on the arm and shoulder. With guidance and assistance from Glenrose Hospital, the intern will collect a library of typically prescribed motions of the shoulder and arm during physical therapy. He will then develop a mathematical model to represent the kinematics of the arm and shoulder as well as a parameter identification routine to identify the model parameters using simple moves and coordinate measurement techniques.

Ultra Wide Band Antenna Design for Microwave Breast Imaging

Existing screening techniques for detecting breast cancer like X-ray Mammography, Magnetic Resonance Imaging (MRI), and Computer Assisted Tomography (CT) have some drawbacks, such as the inability to detect cancer at early stage, over sensitivity or requirement of breast compression. A new approach that has the potential to overcome these shortcomings is Ultra Wide Band (UWB) microwave imaging. This imaging method is based on solving Maxwell’s equation to determine dielectric properties profile with known electric field measured by antennas surrounding the breast.

Co-registration of Nuclear Medicine Images with Anatomical Images for Attenuation Correction and Localization of Activity

Medical image registration is the task of bringing two images into spatial alignment. Automatic and accurate 3D co-registration of nuclear medicine 3D image data with 3D anatomical data is crucial for improving the functional image reconstruction through anatomy-based attenuation correction. Co-registration is also important for the fusion of anatomical data with functional information. Most registration methods involve optimizing an intensity-based similarity metric that is defined by the transformation parameters.

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