The Functional Resilience Question-AIR: Validation of an assessment tool designed to measure employee resilience

The purpose of this research is to validate the Functional Resilience Question-Air (FRQ; Kinley, 2016), an assessment tool based on scientific principles that use the latest research on resilience and neuroplasticity. Specifically, the Functional Resilience Question-Air identifies employees’ personal strengths, providing them with a global resilience score as well as a personalized development plan.

Real Time Inverse Scattering for Optical Coherence Tomography - Year two

A critical challenge today in neuro-surgery is the determination of tumor boundaries intraoperatively. There are means of doing this using high-resolution MRI machines, however, these can be prohibitively costly. Optical coherence tomography (OCT) offers a promising, cheaper, label-free alternative. However, the basic models used for clinical, real-time OCT limit its usefulness and depth of focus. This work will develop a type of image reconstruction that includes digital focusing and anisotropic properties.

Improving obesity prevention and management in primary care: Patient experience of personalized assessment and care planning and impacts on patient self-management

Over 14 million Canadians live with overweight or obesity. Patients want conversations with their primary care team about weight and create personalized plans to improve their health. Primary care clinicians want to have these conversations too, but don’t know how. This project partners with an interdisciplinary primary care team (ESPCN) and the Canadian Obesity Network (CON) to create an intervention for personalized obesity assessment and care planning, and study how it supports patients in their everyday lives.

Signal Parameter Estimation and Tracking During Atrial Fibrillation Using a Bayesian Time-Delay Estimator

AF is an irregular heart rhythm resulting from abnormal electrical impulses and is the most common cardiac arrhythmia encountered in clinical practice. Ablation therapy has been used to eliminate areas responsible for maintaining the arrhythmia using radiofrequency energy. Targeting the culprit regions usually require accurate estimation of activation times in IEGM recordings. The conventional time domain methods fail to present a precise activation detection method and depend on parameters set by an operator.

Assessment of the Neonatal Lung Using Structural and Functional MRI

Currently available diagnostic imaging tools, such as chest radiography and computed tomography, are inadequate for assessing the lungs of preterm neonates. There is considerable interest in using magnetic resonance imaging (MRI) to monitor lung development in neonates longitudinally, since it is a non-invasive and non-ionizing imaging modality. MRI can potentially detect complications at an early stage and improve outcomes by monitoring the effectiveness of therapy, however, images typically suffer from poor signal and organ motion.

Examining the effects of “Fearless Physical Activity” workshops on physiological and psychosocial health in children with congenital heart disease

The “Fearless Physical Activity” workshops are designed to educate and introduce children with congenital heart disease (CHD) to physical activities that are safe for their health. These workshops will provide opportunities for children with CHD and their families to try new activities and to learn about the benefits of lifelong physical activity, specific to those with CHD. The research project undertaken by the intern will look at the effect of these workshops on daily physical activity, physical activity motivation and self-esteem.

Feasibility Evaluation Study of LifeguardMobile (designed for supported self-management of patients with chronic and complex conditions) - Year two

"Lifeguard Health Networks Inc. (LHN) has developed a secure Virtual Health Assistant application (app), to enhance supported self-management for patients with chronic and complex conditions, by leveraging their network of trusted family and friends, under the direction and guidance of health practitioners.We are conducting a study to evaluate the feasibility of the app and the level of user engagement with this form of supported self-management. This is a non-randomized, interventional study having both objective and self-reported outcome measures.

Assessment of biomarkers for the non-invasive diagnosis of male infertility

Infertility is a health issue that affects over half a million Canadian of childbearing age. Half of these cases are related to male reproductive dysfunctions. While semen analysis provides information about some causes of male infertility, about thirty percent of these cases remains unexplained. In this context, the main goal of our project is to assess the potential of target molecules, which are secreted from the internal organs of the male reproductive system into the seminal plasma, as biomarkers for the non-invasive diagnosis of infertility.

Raman micro-spectroscopy for biopsy for prostate cancer prognosis -Year two

Prostate biopsies can be difficult to interpret using standard pathology techniques. Because cancer can be fatal, the development of technologies providing complementary information could improve current pathology practice resulting in improved patient outcome. Raman micro-spectroscopy is a molecular imaging technique using backscattered light following tissue laser excitation to indicate whether or not prostate samples contain cancer cells. However, this technique is very sensitive to the molecules in chemicals used to process tissue (e.g. paraffin), which greatly limits its efficacy.

Novel Cell-surface Engineering Methods to Increase Immune-tolerance of Allogenic Cell Transplantation

Blood transfusion is required for surgery, for the treatment of traumatic accidents and for patients with disorders that require lifelong transfusion therapy. However, when patients receive “mismatched” blood transfusion, their immune system will attack and destroy red blood cells with surface sugars and proteins that differ from their own. This results in massive immune responses in patients, causing shock and even death.