The analysis of protein-protein interactions is critical for understanding cell growth control, and how aberrant connections contribute
to cancer and other diseases. Mass spectrometry is a critical tool in this field, but sample complexity, instrument dynamic range and
resolution limit some applications. This project will evaluate the use of the SelexION ion mobility device and High Resolution TOF
with Zeno pulsing for enhanced separation and detection of cross-linked peptides from protein complexes and to detect posttranslational
modifications of proteins, specifically phosphorylation.
Blockchain is an emerging technology that has the potential to change the way financial participants transact with each other. It enables direct transfer of value and financial assets between participants over networks without the need for a central authority (internet of value). It does this by combining the functionality of different technologies - distributed systems, smart contracts, mutual consensus verification, and cryptography. Given its potential Scotiabank is investing in technical research and business application.
TurnMeUp is an iOS app for always-on voice communications. Users leave the app running in the background and can talk to the recipient (also using the app) at any time. This app is especially useful for coworkers listening to their own music in the background without needing to enter and exit voice call sessions manually. To conserve bandwidth and ensure that users listen to music without being unnecessarily interrupted, TurnMeUp sends voice signals to the recipient only if the user is speaking.
We are conducting research on using techniques from Artificial Intelligence (specifically Machine Learning, Reinforcement learning, and computer vision) to automate the ability of a robotic arm equipped with a hand-like gripper to pick a wide variety of items. The robot uses the visual scene, provided through cameras, in order to choose which item to pick, and needs to then plan and execute a grasp. This is an open research problem at the cutting edge of robotics and AI and we plan to use a combination of state of the art academic research as well as internally developed algorithms.
The company wants to develop a state of art recommendation system for the clients. A recommendation system is a piece of software that provides productsâ suggestions to customers on a website. For example the products suggestions that can be seen on Amazonâs web page are generated by its recommendation engine.
The typical recommendation engines work by utilizing the existing user-product preferences information. They recommend products to a user by comparing his preferences to other similar usersâ preferences. The typical example of this is Users who bought item-A also bought item-B.
Developing a model for a system can come with a lot of uncertainty, especially in the early stages of development. Recent research has be done into removing uncertainty during early stage models. Doctalk plans to use modern research to develop a viable product for market, while contributing to the process of the research being applied to the development of the product.
Using web crawling technology in coordination with state of the art machine learning techniques, the project aims to mine useful, structured information about the worldâs suppliers from the web. Recent advances in artificial intelligence have increased the viability of such autonomous systems for extracting coherent information from arbitrary human-produced content. By leveraging these technologies, our goal is to build improved supplier discovery and recommendation systems.
During surgeries, it is important to keep track of what is happening with the patient, the steps being taken during the surgery by the operating staff, and unforeseen events that occur. All the previous correspond to the surgical workflow. Keeping track of the workflow is essential to achieving a better and safer surgery. In the past, computational tools have been developed to track each step the surgeon takes during the surgery, and dividing the separate surgical phases. However, the adverse events have not been tracked.
The intern will work on applying new advances from the field of Machine Learning to models which make predictions about time-series data. The models have the desirable property modeling the distribution of outcomes in a way that we can sample from, allowing us to account for uncertainty in the modelâs predictions. By making more accurate predictions with more accurate gauges of uncertainty, Electronica will be able to construct portfolios which give more desirable risk-adjusted returns to investors.
Disposable microfluidic devices, also known as labs-on-a-chip, made out of plastic materials have seen increasing applications in chemical and biomedical analysis. In most applications, microfluidic devices usually incorporate small channels and chambers for micro sized dimensions, using heights between a few hundred to a few micrometers. Currently, manufacturing processes have been established to create these sub-millimeter deep features. However, in other applications, higher (or deeper) features of a few millimeters may be needed.