Advanced differential mobility mass spectrometry with electron capture dissociation for the characterization of therapeutic proteins

Many new pharmaceuticals are based on large biomolecules like proteins. Even small differences in the protein structure can cause significant changes in the efficacy and safety of these drugs. Furthermore, these large molecules are difficult to characterize without advanced instrumentation and methods. Current technologies still struggle with robustness and reproducibility. This study aims to introduce new technology to improve the reliability of protein pharmaceutical characterization.

Determination of optimal conditions for the large-scale production of astaxanthin in algae

Astaxanthin is a high-value natural product that is produced by a number of strains of algae. Astaxanthin and related carotenoids such as leutein and zeaxanthin, all derived from beta-carotene, have been demonstrated to have positive health benefits when taken as a dietary supplement. The Myera Group, a Manitoba biotechnology start-up company, has as a primary goal the production of astaxanthin for the commercial market.

PART B- Conversion of CO2 and H2O to Syngas Using Reversible Solid Oxide Fuel Cells (RSOFCs) Technology

The main objective of this project is to demonstrate the highly promising performance of our world-leading catalysts in a scaled-up solid oxide electrolysis cell (SOEC) system. SOECs can efficiently convert the greenhouse gas, CO2, or mixtures of CO2 and H2O, to useful chemicals and fuels, while running on excess electricity, thus serving to store intermittent electricity generated by wind and solar.
The SOECs developed to date in our group are based on a family of new catalysts composed of low cost earth-abundant metals. These cells (ca.

PART A- Conversion of CO2 and H2O to Syngas Using Reversible Solid Oxide Fuel Cells (RSOFCs) Technology

The main objective of this project is to demonstrate the highly promising performance of our world-leading catalysts in a scaled-up solid oxide electrolysis cell (SOEC) system. SOECs can efficiently convert the greenhouse gas, CO2, or mixtures of CO2 and H2O, to useful chemicals and fuels, while running on excess electricity, thus serving to store intermittent electricity generated by wind and solar.
The SOECs developed to date in our group are based on a family of new catalysts composed of low cost earth-abundant metals. These cells (ca.

Portable diagnostic device for outpatient BNP detection - Year two

Heart Failure (HF) occurs when the heart becomes damaged or weakened. HF is an epidemic, with approximately 1 million Canadians affected. BNP is an effective diagnostic and prognostic marker for HF. There is a direct correlation between elevated concentrations of BNP in the blood and the severity of HF symptoms. The need for point-of-care monitoring of BNP levels in the outpatient setting is imperative. The main objective is to develop a portable immunoassay-based electrochemical sensor for rapid detection and monitoring of BNP levels in outpatient’s blood, for early detection of HF.

Development and Commercialization of a Novel Catalyst System for Advanced Electrochemical Oxidation of Industrial Wastewater Pollutants

The aim of this project is to develop a novel catalyst system for treatment of organic and nitrogen containing pollutants in wastewater generated by various industrial sectors. Development of such system is necessary as the discharge regulations are becoming increasingly restricted. The research focuses on electrode design and fabrication that treat toxic wastewater, with an emphasis on the catalyst material, i.e. platinum group metals (PGM) alloys, and mixed metal oxides (MMO).

Beyond the Science of Body Sugaring: Development and Study of Ingrown Hair Treatments

The removal of unwanted body hair by body sugaring is an ancient method commonly used in the middle east, and it is fast becoming the method of choice in North America. When not done properly, the removal of unwanted hair can lead to injuries to the skin and can cause ingrown hairs, also known as razor bumps. Most products available for the treatment of ingrown hairs are often saturated with alcohol, and harsh chemicals that strip the skin of natural oils, often causing burns, irritation, and lacerations.

Real-time Quantitative Analysis of Cannabinoids in Cannabis

The medical marijuana industry has attracted significant attention recently due to its impending legalization in Canada in the coming year. Along with legalization comes the need for accurate and dependable characterization of the components in the product that is to be consumed by the end user. Keystone Labs is a certified cannabis analysis lab with a growing client base. Hence, they are looking to increase their market share by developing a home testing kit that can be used by growers to monitor the plant's chemical composition as it matures.

Synthesis of diamond and diamond-like films

This project is geared towards the development of a cost-effective method to fabricate thin films of carbon materials, such as diamond. The idea is to use solution-based methods coupled to electrochemistry to produce the films. Avenues for the deposition of the film on surfaces of arbitrary shapes will also be explored.

Hydrolytic de-polymerization of hydrolysis lignin using alkaline catalysts: effects of process parameters and optimization

Hydrolysis lignins (HL) are a byproduct from acid or enzymatic biomass pretreatment processes such as the ones employed in cellulosic sugar and/or ethanol plants. They are mainly composed of lignin , unreacted cellulose and mono and oligosaccharides.

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