Understanding the impact of changes to blood donation deferral screening and criteria for men who have sex with men

Available evidence suggests that up to 71% of individuals will require blood or blood products at some point in their lives. To meet this demand, Canadian Blood Services estimates that approximately 100,000 new donors are required annually. However, current blood donation guidelines in Canada require a 3-month deferral period for men who have sex with men (MSM) due to the elevated incidence of HIV in this population, guidelines many see as discriminatory. Given the the improvement in HIV testing technology in recent years, re-evaluation of these guidelines would optimize donor eligibility.

Harm reduction-based programming and services for people living with HIV/AIDS (PLHIV) in a novel clinical care setting: the opportunities and challenges for clinicians, clients, donors and fundraisers

Substance use significantly impacts the health and health care of many people living with HIV/AIDS (PLHIV), especially those dealing with additional medical, psychosocial, and economic complications. The need for comprehensive care for this population is particularly important given the current opioid overdose crisis in Canada. In response, harm reduction (HR) services (e.g., supervised injection, naloxone training, etc.) have been implemented to reduce drug-related deaths and harms. However, such services are typically not provided within hospitals/outpatient programs.

Resistant Starch Prebiotic Effects in Chronic Kidney Disease (ReSPECKD) study

Chronic Kidney Disease (CKD) is associated with a reduced quality of life and an increased risk of kidney failure, cardiovascular events, and all-cause mortality. The goal of this project is to investigate whether the consumption of resistant potato starch (RPS) in addition to current standard care for CKD will reduce uremic toxins and symptoms by altering gut microbiota in patients with CKD. Strategies to reduce the production of these toxins by the gut microbiome in patients with CKD are highly desirable because they may lead to reduced symptoms and delay the onset of dialysis.

Evidence based delivery of effective packages of health services in humanitarian, fragile and conflict affected settings

Maternal, and childhood mortality and morbidity rates continue to rise in conflict affected areas. The Canadian Red Cross (CRC) is collaborating with the International Committee of Red Cross (ICRC) to implement Advanced Health Partnership (AHP) framework to provide health care to populations directly in war zones and conflict settings, without access to healthcare as a result of conflict.

Machine Learning to Predict Temporomandibular Disorders Risk from Genotypes

The goal of this project is to develop new machine learning methods and computational strategies to mega-analyze data from well-characterized datasets on chronic pain conditions to develop a genetic predictive tool. This tool will be implemented in an online interactive dashboard and used by the Quebec Pain Research Network (QPRN) community.

Evaluating and optimizing rural and urban lesbian, gay, bisexual, transgender, queer, intersex, and Two-Spirit (LGBTQI2S) engagement with hospice and palliative care in the Island Health Region

Existing research focused on the experiences of gay and lesbian older adults with the health care system report that there is a general distrust and reluctance to access healthcare based upon the cumulative effect of discrimination over the life course. At present, while 75% of Canadians have indicated they would like to die at home, 45% of Vancouver Island residents die of in acute care. Clearly there exists a service gap and it appears possible that such a gap may be larger in the LGBTQI2S community.

Exploration and Development of an Active Assisted Living Data Sharing Infrastructure Aimed at Supporting the Development of Standards, Guidelines, and Certification Programs – Blockchain for Consent Management

The Ubiquitous Health Technology Lab (UbiLab) will explore the development of a data integration framework and recommendation for associated standards that aims at combining data from (1) smart home systems, (2) AAL or IoT for health technology, (3) mHealth, and (4) wearables. Important areas of data management will be explored, as for example security and encryption (blockchain) for consent management and data management.

Self-sovereign identity data of persons living with dementia at risk of getting lost: how can personal data be protected, owned by individuals, and used to keep dementia clients safe, and inform research and policy?

Three out of five Canadians with dementia wander, raising concern as to how it can be managed. Current information describing best practices to find missing persons living with dementia however, is inconsistent and can cause police difficulty in choosing search and rescue strategies for this population. The purpose of this project is to develop and promote the exchange of best practices to quickly find a lost person with dementia through the development of a guideline. It will involve a literature review and surveys with police across Ontario.

Molecular characterization, autogenous vaccine manufacturing and vaccine potency studies of two pathogenic Avian Reovirus (ARV) field isolates from the Province of Alberta – Part 2

Avian Reovirus (ARV) is an economically important virus that is affecting poultry flocks in Alberta. Birds infected with pathogenic ARV may develop a disease named viral arthritis/tenosynovitis which is characterised by lameness, swollen joints, rupture of tendons and increase mortality. The disease is controlled by parent stock vaccination with live and/or inactivated antigen to provide passive immunity to the chicks. As local strains have been found to be different from commercial vaccine strains, protection can only be achieved with vaccines made from local strains.

The Epidemiology of Fabry Disease and Metabolic Acidosis in Manitoba

The proposed project is for the postdoctoral fellow to access healthcare data for individual adults in the province of Manitoba in order to: 1) determine the rates of metabolic acidosis in Manitoba along with associated outcomes and risk factor profiles and 2) identify patients in Manitoba who are at high risk of Fabry disease but currently undiagnosed in order to facilitate disease screening and improve patient care.

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