Improving implementation of the intensive lifestyle intervention and accuracy of lifestyle data collection in the REMIT-Dapa trial.

Type 2 diabetes (T2D) results in high blood sugars and can cause serious complications. Recent studies suggest that treatment with diabetes medications along with lifestyle changes can result in patients not needing diabetes medications for months or even years, a concept known as diabetes remission. The Remission Evaluation of Metabolic Interventions in Type 2 Diabetes (REMIT) pilot trial was done to look at the effect of lifestyle changes and diabetes medications in people with T2D.

Process and product development of NaquaPureTM, a sustainable novel nano technology for the removal of heavy metals in industrial wastewater

NB-BioMatrix Inc. (NBBM) has developed a magnetic chitosan nanoparticle product, Naqua PureTM for industrial heavy metal water remediation. Unlike current heavy metal removal technologies, Naqua PureTM is cheap, environmentally friendly, requires a low energy input, and is highly efficient.

Rapid Health Impact Assessment On Introducing Permanent High Occupancy Vehicle Lanes and High Occupancy Tolls Lanes In the Greater Toronto Area

The WHO defines health as “a state of complete physical, mental and social well-being and not merely the absence of disease or infirmity”. The holistic nature of this definition provides the basis for an all-encompassing evaluation of health, which is the guiding principle behind health impact assessment (HIA). An emerging area of public concern in Canada is the assessment of the potential impact that transportation infrastructure has on human health. HIA is ideally placed for such an assessment.

Management of posttraumatic stress disorder: a multiple treatment comparison meta-analysis of randomized controlled trials

Traumatic events such as work related accidents, injuries or assault may result in the development of post-traumatic stress disorder (PTSD). This condition is associated with sleep disruption, nightmares, anxiety, and avoidance of the environment where the traumatic event occurred. Significant proportions of patients diagnosed with PTSD are disabled from working; however, little is known regarding which treatments are most effective for improving functional recovery. Existing research mainly focuses on the effect of treatment for reducing symptoms, and looks at treatments in isolation (e.g.

My Wellness Journey: A Health Promotion Study for Children and Youth with Disabilities

The purpose of this project is to support the development of wellness-focused interventions, including weight management, mental health and social well-being for children with intellectual and developmental disabilities (IDD). To date, the focus of health promotion interventions have primarily focused on typically developing children and adolescents, rather than those with IDD.

Unseen Enemy: Global Pandemic Knowledge Mobilization

Our deadliest enemies are the ones we cannot see – viruses or bacteria that lurk and mutate, and grow in resistance, until they become an unstoppable pandemic. This year four interns will work alongside the Tech Samurais company to produce key communication tools that will make effective interventions into the Canadian and global conversation about pandemics. Tech Samurais will be providing access to an unparalleled content library, featuring film from the frontlines of the fight against Ebola, polio and measles.

Developing Tools to Evaluate the Effectiveness of NGO WaSH Interventions in Low to Middle Income Countries

H2O4All is one of many small, non-governmental organizations (NGOs) working to address the needs of the 663 million who lack access to safe drinking water and the 2.4 billion who are without access to sanitation facilities in low- and middle-income countries. Unfortunately, evaluation of water, sanitation, and hygiene (WaSH) interventions are rarely a priority for NGOs like H2O4All whose projects are time and budget sensitive; this is concerning because without evaluation we cannot determine H2O4All’s impact on the communities in which it works.

Scalability of a low-polluting semi-gasifiercookstove and fuel intervention in theTibetan Plateau

Almost half of the world’s population cooks with highly polluting stoves and household air pollution (HAP) is one of the leading environmental risks for global health. Current efforts to reduce HAP have focused on improved cook stove and/or fuel interventions. However, most previous stove interventions failed to achieve reductions in air pollution exposures due to a combination of technological, affordability, and behavioural problems.

Delivering evidence-based health care to children with common health conditions and their families using technology

The MITACS student will join in a large and diverse research group that has developed and disseminated national programs with the use of technology (e.g., computers, internet, smartphones) to treat health problems in children and adolescents, through the following programs:

Clinical programs for Disruptive Behavior, Anxiety, and Enuresis: These programs are being delivered as evidence-based service to children and families seeking help for mental health over the phone and internet, or paper-based manuals.

Statistical challenges in individual patient data meta analysis

In a typical meta analysis, estimates of the parameter of interest (e.g. odds ratio) are extracted from the literature or by contacting researchers and pooled together. In contrast, for IPD-MA line-by-line patient data are obtained from each study.
IPD-MA data permit researchers to define exposures and outcomes consistently across studies, and to analyze the association of interest consistently (e.g. adjusting for the same confounders), which may minimize heterogeneity. IPD-MA are of particular value for synthesis of observational studies.