Budget impact analysis of Rapid Endovascular Treatment of Ischemic Stroke

The return on investment for medical imaging, interventional radiology, is not well understood, with limited existing research on the value realised from the funds spent. It is expected that the Hot Stroke Intervention by interventional radiologists will not only add direct value to the health care system but will have far reaching and significant impact on the Canadian economy. According to the Canadian Heart & Stroke, an estimated 62,000 strokes occur in Canada each year – one every nine minutes. More than 400,000 Canadians are living with long-term disability from stroke.

Training response of elite athletes using heart rate variability and low-frequency fatigue

This research aims to understand athlete recovery and training adaptation by monitoring athlete fatigue. The research will have a direct impact on multiple podium-performances in both Summer and Winter Olympic and Paralympic athletes since knowing how fatigue is present in athletes can help to improve training prescription; specific training prescribed during varying periods of fatigue and recovery can maximize the training response and likely improve performance.

Comparative effectiveness, and network meta-analysis of pre-insulin oral hypoglycemic drugs in the treatment of type II diabetes

The proposed project is two-phased. The first phase involves a study that will use specialized research analysis techniques to compare the effectiveness of pharmaceutical drugs used to treat type II diabetes and to identify if a group of drugs are producing similar benefits in terms of controlling the disease. The applicant’s clinical and epidemiological background would bring value to our study design for this and future projects. The second phase involves economic cost modeling that will forecast financial implications of study findings.

Enhancing exercise capacity and performance in elite Wheelchair Rugby athletes

This project aims to assess a number of novel exercise training techniques to improve exercise performance in elite Canadian Wheelchair Rugby athletes. The first training technique to be assessed is training in the heat, a condition that many Wheelchair Rugby players may have difficulty competing in, to lead to adaptations that will improve performance in the heat. The second is to train athletes using a combination of arm cycling and passive leg cycling to increase the hearts response to exercise and induce changes in heart structure & function and potentially exercise performance.

Understanding the Impact of Fontan Circulatory Repair on Brain Blood Flow Health

Children born with an absent or ineffective right or left ventricle (single ventricle) have a low life expectancy and will undergo at least three surgical procedures ultimately leading to the Fontan Procedure (FP), which allows blood to travel directly to the lungs (bypassing the heart) to become oxygenated. Adolescent FP-patients indicate poor cardiovascular health which in turn could challenge brain blood flow, thereby affecting cognitive capacity and increasing risk of stroke. FP is a relatively new procedure and long-term effects on brain health are unknown.

A Survey of Ergonomics Education Opportunities Available to Dental Hygienists in Ontario.

Dental hygienists (DH) are exposed to many potentially injurious physical demands, such as prolonged exposure to awkward neck, trunk, and shoulder postures. The prevalence of musculoskeletal disorders in this group is alarmingly high (62-93%). DH would benefit from ergonomics-specific workplace safety education, but it is unknown what sort of instruction, if any, is currently offered within the DH curriculum or for continuing education credit. Evaluation of existing educational opportunities will be conducted using a web-based survey of DH across Ontario.

Impact of a Year-Long Physical Literacy Structured Recreation Program on the Motor Proficiency of Kindergarten Students

The study focuses on the assessment of motor proficiencies of children before and after their involvement in a specialised recreation program, when compared to children of the same age who are enrolled in standard parent-selected programming. The specialised program sets at  introducing children to a wide array of activities in multiple environments, and are taught by instructors who have sound knowledge bases in these activities and sports.

Autonomic control of thermoregulation during exercise in spinal cord injury

In able-bodied individuals, increases in core temperature during exercise are controlled by the nervous system as a sweating response. However, individuals with spinal cord injuries (SCI) may have altered sweating responses due to autonomic dysfunction, leading to increased risk of heat stress during exercise. Currently, standard tests do not fully describe how temperature regulation is impaired following SCI. The purpose of this study is to determine whether tests of autonomic function can predict temperature dysregulation in individuals with SCI.

Design and validation of a novel peptide immunotherapeutic for the treatment of dog allergies

Adiga Life Sciences Inc. developed a novel immunotherapeutic platform in which small components (peptides) of allergen proteins are identified and administered in a regimen that causes immune cells to become non-responsive towards the allergens. In a phase II clinical trial, the cat allergy treatment developed by Adiga using this platform reduced allergic symptoms in allergic subjects. However, the mechanism of action of the peptide treatment is still not fully understood.

Ergonomic Design of an Automotive Material Sequencing Centre - Year two

The Ford Motor Company is bringing 800 jobs into the Oakville Assembly Plant. These jobs will be concerned with sequencing parts for the new Material Sequencing Centre. To ensure that workers remain healthy, and their
productivity and quality output is up to Ford's high standards, Ford (through this fellowship) wants to establish clear ergonomic guidelines for this type of work. The post-doctoral fellow will conduct surveys in the plant, as well as review existing ergonomic guidelines within Ford.