Personalized and precise treatments are the keys to improve prognosis of cancer patients and are also the main strategy of Sunnybrook Hospital. This project aims to stratify patients with colorectal cancer liver metastases (CRM) based on their disease subtype and risk using magnetic resonance imaging, which is routinely used in the diagnosis, staging and operative planning.
From its particular focus on HIV/AIDS, Remediating the AIDS Archive looks to historical methods of activist information-sharing through filmmaking and film festivals. This project is not simply historical in nature, however. It also interrogates the ways in which the history of HIV/AIDS is remembered through LGBT2Q+-based cultural representation, the ways in which the HIV/AIDS crisis persists today, and the ways in which media activism continues to address the crisis. To do this, the project uses archival research about the history of four Canadian LGBT2Q+ film festivals.
Persons with primary biliary cholangitis (PBC) have high rates of liver disease-related symptoms and poor health-related quality of life - amongst the lowest of all chronic liver diseases. Patients and the Canadian PBC Society have identified the need for self-care tools to manage symptom burden.
Roquette, the fifth largest global producer of food ingredients, is building the world's largest pea processing plant in Manitoba. Pea protein is a plant-based alternative to animal protein, which is used for many applications, particularly for improving health by replacing fats and sugars. The objective of this clinical study is to determine whether pea protein is equivalent or better than whey protein for retaining muscle in persons on a weight loss regimen.
North America is experiencing an unprecedented opioid overdose epidemic driven by the proliferation of fentanyl and fentanyl-adulterated drugs. Based at the BC Centre on Substance Use (BCCSU) and in collaboration with the BC Centre for Disease Control (BCCDC), I will undertake an ethno-epidemiological study to evaluate the implementation, uptake, and effectiveness of a novel low-barrier hydromorphone distribution program via a secure automated medication dispensing system targeting individuals at high risk of fatal overdose.
Antimicrobial resistance is a recognized and growing problem in equine medicine. Mesenchymal stromal cells (MSC) have recently been shown to have antimicrobial properties. We are interested in exploring if equine MSCs can reduce bacterial growth in vitro and to understand the cellular mechanisms governing such an effect.
The proposed project seeks to better understand and study the effective application of data processing tools and quality assurance systems in clinical research. Data from clinical trials is crucial in the pharmaceutical industry because it provides indicators of safety and efficacy of drug treatments for patients. However, processing and reporting on the large amounts of data available has become increasingly difficult, especially for organizations that run complex trials in an international setting.
The main objectives of this one-year study are to enhance systems in data management and integration in three ways: 1) create secure networks that can support BYOD; 2) create a data pipeline system for ETL; and 3) integrate ML content generation into a content management system. An Agile methodology will be used to plan and implement the projects on which the interns will work. This approach is widely used in software development and is based on collaboration, continual improvement and adaptation.
There is a growing need for law enforcement agencies and safety sensitive workplace environments to be able to evaluate impairment. Impairment due to mental cognitive deficits, drugs or alcohol use, prescription medications, or fatigue could all limit a person’s ability to perform a hazardous task safely.
Current testing tools utilize saliva, breath, blood or urine to measure levels of substances that may impair a person’s judgement. These types of tests are invasive, and in many cases not reliable.