Developing an aptamer, graphene based electrochemical biosensor for early detection of Alzheimer disease.

At least 50 million people are living with Alzheimer disease (AD) worldwide and the number is estimated to grow to 150 million by 2050 making it a global epidemy. AD in the sixth cause of death in north America and its estimated cost of caring is $277 billion yearly, yet no cure is available for AD. This is partly because current diagnostic techniques are expensive- ranging from $1500 to $6000- or invasive- require lumbar punctures-, which makes early screening and disease monitoring difficult.

COVID-19 and long term care workers: Staffing shortages and diverse pathways to entry

The goal of this project is to enhance health workforce planning in the Waterloo Region in collaboration with the Workforce Planning Board of Waterloo Wellington Dufferin (WPB), to address the Long Term Care staffing crisis by providing quantitative analysis of the demographic make up of the labour market involved in health relation professions, which will identify the demographic specifics of this population in terms of immigration status, length of residence in Canada etc.

Strategic Management - Transitioning from the Red Ocean to the Blue Ocean: A Case Study of Blueprint Residential Property Management Company

This research is intended to assess Blueprint Residential Property Management Company's current organizational structure, business processes, system infrastructures, policies, leadership skills, and employees to determine areas of change and realignment to move the organization to a leading-edge service company. The research is also intended to factor in opportunities that need to be tapped into due to the impact of the global COVID-19 pandemic and recent Bill-20 legislation passed by the Government of Alberta.

Understanding the Operational, Human, and Policy Implications for a Roadmap to Canada’s Next Generation 9-1-1 Services

The project will create a research-based strategic plan and roadmap that describes when and how to best introduce NG-911 services in British Columbia. The research needs to consider the unique BC context including review of current legislation, our emergency response structures and practices, current technologies, societal expectations and political norms. The work also needs to consider global trends and developments in emergency communications from industry, government and emergency response agency perspectives and identify the implications in BC.

Awechigewin: Developing a Virtual Approach to Community-Based Planning with Michipicoten First Nation

The proposed research project will use a combination of Participatory Action Research and Indigenous Research Methods to create an online engagement tool to gather Michipicoten First Nation (MFN) member’s perspectives on draft planning strategies and policies regarding six priority areas. Engagement is a challenge for MFN as a displaced and widely dispersed community, challenges which are heightened by the COVID-19 pandemic. Online engagement is an important tool for reaching Michipicoten citizens on- and off-reserve, particularly during the pandemic.

Livelihood Fisheries and Indigenous Rights in Atlantic Canada: An Examination of Netukulimk Principles in Action

The Atlantic Policy Congress of First Nations Chiefs Secretariat’s (APC) Fisheries and Integrated Resources Department is responsible for research, analysis, and development of policy altneratives and programs for all aspects of fisheries for their member communities. This research project examines the role of Indigenous principles for resource management in the fisheries operations of Indigenous communities in Atlantic Canada.

Impact of heat accumulation pattern on the enological potential of Vitis sp. berries

Over the years, consumption of wine has been a lifestyle of many Canadian households, with majority of these wines imported from outside Canada. On the local market, Canadian made wine competes with sometimes century-long wine producing countries (e.g. France, Italy, Spain) that are carefully selected by importers (SAQ, NSLC, LCBO, etc.). With this gap in the Canadian wine market, there is the need to expand the Canadian grape industry towards the production of wine with high market value to increase its share on the local market.

Single-molecule analytics of RNA/DNA drug constructs interacting with RNA targets and with lipid nanoparticle delivery vehicles

In this project, the interns will develop a new set of tools and techniques to provide new scientific insights into the detailed interactions that occur between drug and target molecules in the human body. Understanding of these interactions is critical to design better, more effective, and more precisely targeted drugs. The problem is that current techniques for investigating molecular interactions make “ensemble measurements” over huge numbers of drug and target molecules and give researchers only an “average” measurement of the interactions.

Stability Testing for Cannabis Products

Understanding the stability profile of a product, whether a consumer packaged good or a pharmaceutical drug product, is key to ensuring the consumer has a safe and effective product. In the pharmaceutical realm, the internationally accepted approach to stability testing is codified within the International Conference on Harmonisation (ICH) Guidance: Q1A(R2) (Stability Testing of New Drug Substances and Products) and Q1B (Stability Testing: Photostability Testing of New Drug Substances and Products).

Financial Portfolio Reconciliation using Deconstructed Deep Learning

Citco provides financial products and services to hedge funds, private equity and real estate firms, investors, institutional banks, Global 1000 companies, and high net worth individuals in the Netherlands and internationally. The previous research was focused on optimizing operations by automating trade resolution and reducing risk using machine learning. Given its success in matching individual transactions, the proposed project plans to extend the research to overall portfolio management for identifying discrepancies in the portfolio at the end of the trading day.