Establishing a Standard of Proof for Public Health Threats: Exploration of the Use of Precaution and Weight of Evidence

Emerging public health risks are typically characterized by uncertainty in the evidence-base (i.e., a mosaic of clinical, laboratory, and/or epidemiological evidence, that is often unclear and not uncommonly conflicting). Given this uncertainty, it is often difficult for decision-makers to discern if action is warranted. The question of how compelling the evidence base ought to be in order to warrant action points to our topic, namely the question of a standard of proof (i.e., related to policy creation/ governance and the assessment of evidence).

Understanding Toronto’s Historical Watercourses

Today almost 3 million people live in Toronto (almost 6 million in the Greater Toronto Area). As the city's population continues to grow, people are increasingly seeking connection to the natural landscape within the city limits. This project will illuminate and re-invigorate understanding and appreciation of the natural history of the area and the importance of connected waterways. It will inform future planning related to the connection between natural and engineered water resources in an urban environment.

Respiratory Health System and Pandemic Early Warning System

The goal of this project is to develop a low-cost ventilation system which accurately detects and records both patient treatment data and environmental data is in great need. Further, such a system will allow to create a global health map. This research and resulting hardware and software will not only benefit the current research of COVID-19, but also assist in the long term identification and management of potential respiratory pandemics.

Development of an optical sports monitoring sensor and method for non-invasive evaluation of muscle metabolic fitness and function in elite athletes

Currently, elite athletes and their coaches rely on the subjective self-awareness and measurement of muscle force, heart rate, and the amount of blood lactic acid level to monitor body fitness and athletic performance. These methods, however, are not ideal and always reliable due to subjective errors, technological limitations and individual confounding factors that limit the validity and accuracy of the measures. Furthermore, current methods are not able to monitor muscle function and fitness during exercise and recovery periods.

Proof of concept testing of a bead-on-string polyacrylonitrile nanofibrous air filter for indoor air cleaners

Indoor air quality of buildings is becoming even more important today, with the persistence of COVID-19 pandemic. A new type of air filter, based on bead-on-string polyacrylonitrile, offers high ultrafine particles removal (above 99%) as well as low pressure drop. Environmental and Power Solutions and Canada Water Technology eXchange are joining forces to undertake research to investigate options to control COVID-19 virus.

ALS in a dish: development of an in vitro human 3D model of the neuromuscular junction with functional readouts

In amyotrophic lateral sclerosis (ALS), the communication between motor neurons and skeletal muscle is lost, resulting in weakness and degeneration of muscle tissue. ALS animal models fail to reproduce the complexities of the disease, which is thought to account for the failure of new drugs in clinical trials. At The Neuro, human blood samples are obtained to generate pluripotent stem cells (PSCs), which are able to give rise to all the cell types of the human body.

Novel, Low-Cost COVID-19 Point of Care Monitoring and Triaging Device

Testing for COVID-19 is a major strategy to manage the pandemic and one of the most important criteria and measures that are needed to restart the economy in Canada (First Ministers' statement on shared public health approach to support restarting the economy, April 28, 2020). Two types of diagnostic devices are commonly used: 1) Lab-based devices and 2) Point of Care (PoC) devices, which are mobile solutions that can be used at homes, in doctors' offices and long-term care homes. Only one nucleic acid-based PoC device is authorized by Health Canada to date.

Algorithmic and Interface Advances in Computer Algebra

Computer Algebra Systems (CAS), with their unique ability to analyze and solve mathematical problems, are gathering new communities of users, who challenge them with more and more complex tasks. It is necessary, therefore, that the core engines of CAS implement state-of-the-art algorithms. At the same time, CAS need to build new bridges to specialized software and to develop interfaces to emerging research areas.

Supporting Municipalities in Newfoundland and Labrador in navigating COVID-19

As a result of the COVID-19 pandemic, Municipalities in Newfoundland and Labrador have faced and continue to encounter challenges. They are also exploring new opportunities as they navigate what appears to be a new municipal world. Municipalities Newfoundland and Labrador (MNL) is working with its members on this navigation through regular engagement, survey work and one-on-one supports. The research question guiding this work is as follows: What are the best municipal practices for safereopening?

Food Convergent Innovation Canada Start-Up:Developing data and methods to support the digital backbone of the agri-food system in the Covid19 context

Food Convergence and Integrity (FCI) Canada is being formed to help agri-food companies mitigate the disruptions of Covid-19, increase interactions and innovations among Canadian agrifood companies and enable new agrifood business streams. Through its member platform, it will enhance resilience and competitiveness of the Canadian agri-food sector, resulting also in increased food security for Canadians.

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