Connecting watershed-scale land-use with coastal wetland ecologicalintegrity: The tributary – coastal wetland nexus in Durham Region

Coastal wetlands and embayments are sensitive ecosystems located between rivers and the shoreline of lakes. Human activities (e.g., urban development and agriculture) on land can influence the functioning of these ecosystems and the quality of water that flows through them. Healthy coastal wetlands can offer significant services in the form of water quality purification, flood control, and storm surge protection, as well as provide important habitat for wildlife.

Localized cooling of the lower body to maintain core body temperature in Paralympic athletes during heavy exertion

Localized cooling of the lower body to maintain core body temperature in Paralympic athletes during heavy exertion

Microwave Radar System for Stand-off Hazardous Gas Detection and Material Characterization

This project will advance development of technologies capable of detecting rapidly and reliable a range of gases harmful to humans. Student interns working in university labs and with our partner will develop new gas sensors using new materials that resonate in observable ways when they come into contact with harmful gases. These sensors will be small and extremely durable, potentially worn on garments or attached to workers’ tools.

Identifying the Key Factors in Adopting Digital ID Service and Profiling the Early Adopters

Despite the digital transformation going on around us, the methods of proving our identity remain locked in a traditional physical mode, with paper or plastic documents, and the reliance on these traditional modes of proving identification and authentication is becoming a significant barrier to innovation. Therefore, creating a digital identity and authentication method that is highly secure, ubiquitous and convenient is necessary. A new digital identity system will allow us to do things online that we have traditionally used physical ID for.

Machine learning-based optimization of a small-molecule suppressor of the cellular prion protein

A reduction in the levels of the cellular prion protein (PrPC) is expected to ameliorate cellular toxicity in both Alzheimer’s disease (AD) and prion diseases. The latter are invariably fatal diseases that include Creutzfeldt-Jakob disease in humans and bovine spongiform encephalopathy (BSE), also known as ‘Mad Cow Disease’, in cattle. To identify a rational method for reducing PrPC levels, the Schmitt-Ulms group has been studying the evolution, function and molecular environment of PrPC for more than ten years.

Visualization Analysis of eBus Routes and Facilities

The adoption and integration of electric buses (eBus) will have positive impacts on the efficiency of transportation services, on energy consumption and related environmental benefits as well as costs, In partnership with CUTRIC OCAD U will engage dynamic Visual Analytics and Design Science to support electric bus (eBus) implementation in Canada, allowing the careful tracking of multiple data sources with which to measure the process of adoption, and then providing tools for monitoring of services, and prediction of impacts. We will further research on visualization technologies.

Development of MCT4-targeting small molecule inhibitors for management of castration-resistant prostate cancer

Late-stage, therapy-resistant prostate cancer (PCa) remains a difficult-to-treat disease that urgently needs better therapeutics. Advanced PCa cells use glucose (sugar) differently than normal cells, substantially increasing lactic acid secretion into the surrounding environment. This supports cancer growth in numerous important ways, including helping PCa avoiding destruction by the patient’s immune system. One critical protein involved in this process is MCT4, which transports lactic acid out of cells.

Understanding Montreal festival soundscapes

Quartier des spectacles is a dense multi-cultural hub with large outdoor festivals, also housing an ever-growing residential population due to new high-rise development projects. Given the need to balance vitality with quality of life, this project focuses on expectations of residents and festivalgoers in terms of their sound environment.

Nutrient removal using a solid state glass adsorbent for treating agricultural waste, waters, and public effluents

Agricultural waste and public effluents often contain elevated levels of phosphorous and nitrogen that limit its ability to be directly repurposed as crop fertilizer or irrigation spray. Removal of soluble nutrients from waste water is difficult. Current treatment options have high investment costs and are often not well suited for smaller farm sizes common in Canada. This research intends to characterize the utility of a solid state absorbent material engineered by NPower Clean Tech Corporation that shows promise for removing anionic forms of phosphorous and nitrogen.

A reconciliation of the top-down and bottom-up approaches to risk capital allocations

Two overarching approaches to allocate the aggregate risk capital stand out nowadays. These are the top-down approach that entails that the allocation exercise is imposed by the corporate centre, and the bottom-up approach that implies that the allocation of the aggregate risk to business units is informed by these units. Briefly, the top-down allocations start with the aggregate risk capital that is then replenished among business units according to the views of the centre, thus limiting the inputs from the business units.