RFSoC readout development for massively scalable kinetic inductance detectors

This project covers the development and validation of electronics designed to operate large arrays of superconducting sensors used for experimental astrophysics experiments. These sensors have strict requirements for signal processing and noise, making them challenging to operate at scale. However, the next generation of astrophysics instruments will require tens-to-hundreds of thousands of such sensors. The research to be carried out in this proposal includes the prototyping and validation of hardware and signal processing algorithms intended to meet these challenges.

Evaluating the efficacy of a 91-day self-talk mental health self-care journal

Self-talk describes our inner monologue, or “inner voice”, that we are often conscious of. This self-talk can be important and helpful, such as when it is encouraging us, calming our fears, or giving us confidence. However, often this self-talk is negative, and can make us feel sad, upset, or worthless. There has been a recent surge in the popularity of health-promotive self-care products, or products aimed at providing individuals with “the knowledge, skills, and attitudes required to achieve and maintain good health”.

Evaluating the mental, social, and physical benefits of recreation programming for older adults

Older adults (60+ years) are a growing population in Canada, and recreation provides a valuable opportunity to support and improve the health of older adults. Community recreation centres develop and implement recreation opportunities for older adults, but do not have the tools to track the success of their programs. The purpose of this project is to co-develop an assessment tool for recreation delivery services to evaluate and track the effectiveness of their programs at supporting the mental, physical, and social health of their older adult participants.

A microfluidics approach towards perovskite nanostructures rational design

Metal halide perovskite nanostructures are materials with outstanding photoluminescent properties and very promising in optoelectronic applications. With this project, we seek to explore how several synthesis parameters influence the formation and grow of the nanostructures. We will use a suite of complementary structural characterization techniques that will provide a deep understanding of the near, medium and long-range order, and we will correlate the structural and photoluminescence properties.

Deep Learning Methods for Design of RNA-targeting Small-Molecule Antibiotics

Growing antibiotic resistance is a major threat to global public health. One way to combat this problem is through the development of antibiotics that act against bacteria in new ways. Historically, antibiotics work by interacting with proteins in the bacteria, which are needed for the cells to reproduce. However, recently, it has been shown that molecules that interact with RNA rather than proteins can also inhibit bacterial growth and reproduction.

Cancer treatment using drug-loaded thermosensitive liposomes with non-invasive ultrasound thermal therapy and temperature monitoring and control in an in vivo animal model

Chemotherapy is the most commonly used method for treating different cancer types that involves the delivery of chemotherapeutic drugs, leading to the death of cancer cells. However, the non-uniform distribution of chemotherapeutic drugs within the tumor and systemic toxicity has multiple side effects, and the delivery problem remains unsolved. Drug delivery carriers such as liposomes are used to deliver the drug to the targeted regions. To this end, a controlled and reliable release of the loaded chemotherapeutic drugs from a liposome core has remained a problem to overcome.

Implementations of state-of-the-art quantum error-correcting codes and decoders for simulations of fault-tolerant logical operations

Quantum computers encode information with qubits. Unfortunately, qubits are subject to error. Those are physical qubits, and one will need many physical qubits to create an error-free qubit, also called a logical qubit. In this project, the university and industry researchers will work together to understand if the error rate of a logical quantum circuit will be arbitrarily suppressed by increasing the number of physical qubits. One of the key challenges is to simulate large enough systems necessitating scalable implementations of representation of quantum error-correcting codes and decoders.

Audience Engagement in Virtual/Hybrid Performances

The COVID-19 pandemic has accelerated an increasing dependance on the digital realm, with the performing arts and entertainment industry being forced to reinvent themselves in order to stay relevant. The advent of immersive technologies, such as virtual reality, has provided both artistic and economic potential to create virtual and hybrid shows, but it is unclear how this drastic change in format may impact the viewer’s engagement in the resulting performances.

Automated Scanning Probe Fabrication for Atomic Scale Devices - Year two

With our increasing dependence on technology, the total energy consumption from electronic devices for computation is projected to surpass all other contributions. By creating atomic-scale devices at the fundamental limits in size and energy cost, we can reduce their overall energy consumption while increasing computational power. While proof of concept devices are already routinely created, a fully automated fabrication procedure is necessary to successfully merge this technology with current electronic manufacturing processes.

Determining Biomarkers of Addiction Disorders and Mental Health using Electroencephalography

There is a health crisis in Canada where substance abuse and addiction disorders have been growing out of control, resulting in the death of 19,355 Canadians from 2016 to 2020. Researchers describe the crisis to be getting worse in that opioid-related deaths tripled from 2000 to 2015 in Ontario, Canada and increased by 120% since the onset of COVID-19. Consequently, therapies are struggling to keep up.