The current public health emergency due to the COVID-19 pandemic has changed the way we socialize with eachother, how we access health care, and our economic conditions over a short period of time. For people who are marginalized, these changes may cause decreases in income, loss of social support and community connections, unstable home environments, more substance use withdrawal and overdose, and growing mental health concerns. Some responses to the pandemic, like physical distancing and financial challenges, are likely to last for months.