Development of Additives in Pellet Form For Asphalt Mixes Containing Recycled Asphalt

In this project, asphalt mix additives in the form of pellets added directly in the mix during mixing will be developed. The pellets will include at least recycled asphalt shingles, but other additives like rejuvenators and warm mix additives will also be tested. Those additives should help to make asphalt mixes with better mechanical properties while using less virgin materials. The compactibility, the workability, the moisture resistance and properties like thermal cracking resistance, rutting resistance and modulus of those modified mixes will be tested.

Mevalonate Cascade Inhibition Sensitizes human Glioblastoma Cells to Temozolomide via Modulation of Autophagy

Glioblastoma multiforme (GBM), also known as glioblastoma and grade IV astrocytoma, is the most common and most aggressive cancer that begins within the brain. There is no clear way to prevent the disease. Typically treatment involves surgery after which chemotherapy and radiation therapy is used. The medication Temozolomide (TMZ) is frequently used as part of chemotherapy. Cholesterol lowering drugs (statins) is recently being considered as a novel and safe approach for combination therapies in many cancers.

Diagnostic screening for conscious awareness in brain injury and disease: Visual component

Since the mid 1970s, medical personnel have used the Glasgow Coma Scale (GCS) as an important tool to rate and describe levels of consciousness. This scale is rudimentary and subjective, often resulting in misdiagnoses in cases where people lack the capacity to communicate. In some unfortunate situations, severe neurological damage can render people unable to move. Inevitably, these people are deemed vegetative when in actuality; many are simply ‘locked in’. For years researchers have used cognitive event related potentials (ERPs) with modified EEG to assess receptive language capacity.

Management of posttraumatic stress disorder: a multiple treatment comparison meta-analysis of randomized controlled trials

Traumatic events such as work related accidents, injuries or assault may result in the development of post-traumatic stress disorder (PTSD). This condition is associated with sleep disruption, nightmares, anxiety, and avoidance of the environment where the traumatic event occurred. Significant proportions of patients diagnosed with PTSD are disabled from working; however, little is known regarding which treatments are most effective for improving functional recovery. Existing research mainly focuses on the effect of treatment for reducing symptoms, and looks at treatments in isolation (e.g.

Implementation of a chip-based MDTMA platform for evaluating prostate cancer treatment response and mode of action.

Prostate cancer will affect 1 in 7 Canadian males. While the number of therapeutic options is increasing, matching each patient to the right therapy remains as the challenge for a personalized approach to patient management. Currently, most of the attention has focused on identifying biological tags that can predict patients response. We have developed an alternative approach that can keep tumor samples alive outside the body to test therapeutic agents directly on the tumor.

Tensor network characterization of superconducting circuits

Quantum information processing holds the promise of the next revolution in information technologies. Many implementation candidates are still being investigated. One of them is superconducting circuits. Studying quantum systems in general is a computationally difficult task. If one hopes to build scalable and reliable devices, one must resort to approximate numerical design tools. Tensor networks is one such method that has been used extensively in theoretical physics to study condensed matter systems.

Validation of neurodegeneration screen hits in zebrafish: functional analysis of drug effects on neural activity

The OCE-CQDM Life Sciences R&D Challenge program is a groundbreaking collaboration between researchers at St.Michael’s Hospital (SMH) and Treventis Corporation (both in Toronto), as well as the University of Montreal (Dr. Drapeau, an expert in zebrafish models of disease). The zebrafish is a robust model for translational research because of our understanding of zebrafish biology and its overlap with that of humans.

Landscapes of Erasure: geographies of absence in Michoacan.

The state of Michoacan in Mexico, where most of the drug war comes from, has a long history of exploitation against indigenous people and the natural resources concentrated in the state. Michoacan's vast system of forests has been subjected to years of illegal wood trafficking, a fact very well known but little exposed, pushing the indigenous 'purepechas' to become both slaves and accomplices of those crimes. Drug trafficking clashes with civil war and indigenous resistance struggles with their right for local jurisdiction of culture and natural resources.

China Green Powerhouse

This documentary film on environmental policy in china is an international collaboration with Dr. Wang Xi, the director of the Institute of Environmental and Resource Law at Jiao Tong University in Shanghai, China. Dr. Wang Xi has worked on the amendment to China’s Environmental Law in 2014. This policy-driven research is innovative in its methodological approach to environmental policy, and Canada-China foreign relations in the context of climate change. This research investigates recent efforts to improve China’s environmental protection regulations.

Cultural Capital and Return Migration to Turkey

This research project studies Turkish university professors who have spent significant periods of time living in the United States or Canada but have decided to move back to Turkey. I want to understand why these professors choose to move back to Turkey after spending so much time in North America, and what factors cause them to leave. This project will take place in Istanbul, Turkey with possible trips to Ankara and other cities to meet my subjects. The research will include interviews with twenty-five professors from various backgrounds.

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