In vitro and in vivo evaluation of silicon-based quantum dot nanoparticles

Silicon quantum dots (SiQDs) are semiconductor nanoparticles with sizes ranging from 1 to 10 nm that show great promise for photonics, microelectronics, and fluorescent bio-imaging considering their ability to fluoresce from blue to near infrared light. In comparison to conventional quantum dots (which can release toxic metals), Si quantum dots are expected to be safer and more stable for use in biomedical engineering applications.

This 24-months project aims at evaluating SiQDs for their toxicity both in vitro and in vivo.

Silicon Nanoparticle and Cellulose Nanocrystal Reinforced Polymer Composites

Cellulose and Silicon are two of the most abundant natural materials in the world, thus it is only “natural” to combine the two materials. Specifically, cellulose nanocrystals (CNCs) have been attractive sustainable additives for the mechanical reinforcement of polymers and silicon can be easily converted to silicon nanoparticles (SiNPs) for use in biosensing, coatings, and used as quantum dots in optical films, and medical and display applications.

Exploration of Hydrogen Silsesquioxane (HSQ) Formulations and the use of HSQ as a Precursor for Silicon Quantum Dots for Use in Polymer Coatings - Year two

The project will entail the production and characterization of hydrogen silsesquioxane (HSQ), a useful material for both lithography and production of silicon nanomaterials. This material is the workhorse for Applied Quantum Materials Inc. (AQM), as it is one of their central products that they supply to the e-beam lithography industry as well as the precursor for their silicon nanomaterials.

Exploration of Hydrogen Silsesquioxane (HSQ) Formulations and the use of HSQ as a Precursor for Silicon Quantum Dots for Use in Polymer Coatings

The project will entail the production and characterization of hydrogen silsesquioxane (HSQ), a useful material for both lithography and production of silicon nanomaterials. This material is the workhorse for Applied Quantum Materials Inc. (AQM), as it is one of their central products that they supply to the e-beam lithography industry as well as the precursor for their silicon nanomaterials.

Development of COVID-19 Rapid Diagnostic Test

The current workflow for COVID-19 testing is overwhelmed for many reasons including the need for time-consuming sample preparation, the limited availability of test reagent, and the length of time it takes to complete the test process (approximately 3 hours). As the test-and-trace approach is critical to containing the spread of this virus, rapid diagnostics are crucial. To improve the testing timeline, diagnostic labs need to process samples quickly, which requires the use of automated tests. The use of magnetic bead technology is highly amenable to automation.

Silicon Quantum Dot Trace Explosive Sensor - Year two

The rapid detection of high energy materials (i.e., explosives) and chemical, biological and radioactive (CBR) agents have received substantial attention because of its obvious importance to security and forensics. Applied Quantum Materials Inc. (AQM) is developing a straightforward luminescent quantum dot paper- and/or cloth-based detection system that shows instantaneous optical detection of nitro-based explosives in solution and solid phases at nanogram levels by monitoring the luminescence quenching after being exposed to explosive residues.

Silicon Quantum Dot Trace Explosive Sensor

The rapid detection of high energy materials (i.e., explosives) and chemical, biological and radioactive (CBR) agents have received substantial attention because of its obvious importance to security and forensics. Applied Quantum Materials Inc. (AQM) is developing a straightforward luminescent quantum dot paper- and/or cloth-based detection system that shows instantaneous optical detection of nitro-based explosives in solution and solid phases at nanogram levels by monitoring the luminescence quenching after being exposed to explosive residues.

Silicon Quantum Dot Trace Explosive Sensor

Development and testing of a trace explosive sensor based on silicon nanomaterials or quantum dots. The project will involve interaction and pilot testing with the RCMP and Transport Canada. The success of the project will enable Applied Quantum Materials to introduce a new product into the security marketplace and form a platform technology for the development of drug and chemical agent detection.