Effect of Diesel Exhaust Exposures on the Respiratory Microbiome in COPD Airways

Some of the bacteria present in healthy lungs protect the lung against harmful germs. Studies have shown that people with lung diseases often lack these "good" bacteria in their lungs. Our team has been demonstrated that breathing polluted air causes lung inflammation, which can make it hard to breathe, especially for people who have lung diseases. We think that polluted air could change the lungs’ bacteria.

Radon: Building a BC Based Response - Year two

Radon is a cancer-causing radioactive gas produced by the natural decay of uranium in rocks and soils. Radon can enter buildings and reach high levels in indoor air (Khan and Gomes, 2017). It is the second-leading cause of lung cancer (after smoking). killing approximating 3200 Canadians a year (Chen et al. 2012). High radon concentrations can be easily remedied, and doing so is a cost effective way to prolong life and reduce death from disease (Gaskin, et. al. 2018). However, Canada’s legal rights and remedies to respond to radon in Canada are largely inadequate (Dunn and Cooper, 2015).

Radon: Building a BC Based Response

Radon is a cancer-causing radioactive gas produced by the natural decay of uranium in rocks and soils. Radon can enter buildings and reach high levels in indoor air (Khan and Gomes, 2017). It is the second-leading cause of lung cancer (after smoking). killing approximating 3200 Canadians a year (Chen et al. 2012). High radon concentrations can be easily remedied, and doing so is a cost effective way to prolong life and reduce death from disease (Gaskin, et. al. 2018). However, Canada’s legal rights and remedies to respond to radon in Canada are largely inadequate (Dunn and Cooper, 2015).

Blood biomarkers of asthma

Allergic asthma is a condition of the airways characterized by airway constriction and hyperresponsiveness upon allergen exposure. About half of the allergic asthmatic individuals experience only an acute airway constriction (early response) within several minutes upon exposure to allergen while the other half of individuals experience not only an acute airway constriction but also a chronic airway constriction plus inflammation (late response) within several hours after the allergen exposure. It is not clear why the late response is not developed in all sensitized individuals.