Long-Term Prevention of Catheter Infections Using Chemical Coatings - Year two

Urinary tract infections caused by indwelling catheters (CAUTIs) employed for the treatment of urinary flow are very common. Almost 100 million of these devices are sold on an annual basis with around 25% of these being marketed in the USA. In addition to the cost of catheters and their insertion, hospital treatment of CAUITs runs into the hundreds of millions of dollars every year.

Long-Term Prevention of Catheter Infections Using Chemical Coatings

Urinary tract infections caused by indwelling catheters (CAUTIs) employed for the treatment of urinary flow are very common. Almost 100 million of these devices are sold on an annual basis with around 25% of these being marketed in the USA. In addition to the cost of catheters and their insertion, hospital treatment of CAUITs runs into the hundreds of millions of dollars every year.

Early stage detection of ovarian cancer

Infections acquired through long-term catheter use are a major problem for nearly 20% of all patients. This project seeks to apply Econous Systems’ anti-fouling MEG-OH coating to biomedical plastic catheters to see if they prevent the 3 most common microbes: E. coli, C. Albicans and S. Aureus, f rom growing. This will initially involve in vitro testing using a flow-through model to simulate blood flow, monitoring first static and then dynamic microbe growth using fluorescence microscopy. In vivo testing will follow using rats as a preclinical m

Long-Term Prevention of Catheter Infections using Chemical Coatings

Infections acquired through long-term catheter use are a major problem for nearly 20% of all patients. This project seeks to apply Econous Systems’ anti-fouling MEG-OH coating to biomedical plastic catheters to see if they prevent the 3 most common microbes: E. coli, C. Albicans and S. Aureus, from growing. This will initially involve in vitro testing using a flow-through model to simulate blood flow, monitoring first static and then dynamic microbe growth using fluorescence microscopy. In vivo testing will follow using rats as a preclinical model.