Automated Electrographic Analysis of Cerebral Organoids for Characterization of Pharmacological Intervention

Through our previous work, we’ve been able to take blood samples from patients with genetic epilepsy and make 3D miniature brains (organoids) from their own cells. These organoids then retain that patient’s genetic predisposition to epilepsy, which we can then study in a lab to find the best drug that could be recommended to the patient. This project will help refine the set of electrical properties of the organoids that can be used to make such a prediction.