Sensory Disinhibition, Cognitive Flexibility and the Neural Correlates Underlying Post-Traumatic Stress Disorder (PTSD): A Simultaneous EEG-fMRI Study - Year two

Individuals with post-traumatic stress disorder (PTSD) often struggle to relax, or simply be at ‘rest.’ In particular, recent research has revealed participants with PTSD show hyper-activity across the visual cortex while at rest. Referred to as sensory hyper-activity and disinhibition, altered resting-state patterns are thought to be underlying hypervigilance and re-living sensations clinically, as well as cognitive deficits, which may be produced when cognitive resources are overwhelmed by sensory hyper-activity.

Characterizing Clinical Heterogeneity in Substance Use Disorder Treatment Programs

Research has shown that substance use disorders may have distinct pathologies requiring different treatment approaches. Recently, there has been a growing interest in personalized medicine, which aims to tailor treatment to a patient’s unique characteristics. One strategy for implementing a personalized approach in heterogeneous clinical settings is to identify patients exhibiting common clusters of symptoms. However, these methods are infrequently implemented in psychiatry and addiction care.

Sensory Disinhibition, Cognitive Flexibility and the Neural Correlates Underlying Post-Traumatic Stress Disorder (PTSD): A Simultaneous EEG-fMRI Study

Individuals with post-traumatic stress disorder (PTSD) often struggle to relax, or simply be at ‘rest.’ In particular, recent research has revealed participants with PTSD show hyper-activity across the visual cortex while at rest. Referred to as sensory hyper-activity and disinhibition, altered resting-state patterns are thought to be underlying hypervigilance and re-living sensations clinically, as well as cognitive deficits, which may be produced when cognitive resources are overwhelmed by sensory hyper-activity.

Evaluating the Implementation of Goal Management Training Cognitive Remediation Therapy among OSI Clients in Quebec City

There is an urgent need to address the mounting crisis of mental illness, and in particular posttraumatic stress disorder (PTSD), among military members and Veterans in Canada. PTSD is associated with changes in cognitive functioning across multiple domains (e.g., poor memory and attention) that can negatively impact military members and Veteran. Goal Management Training (GMT) is a cognitive remediation strategy that has been found to improve memory, attention and ability to engage in complex reasoning in individuals with PTSD.

A Novel Cognitive Remediation Intervention for Public Safety Personnel with Post-Traumatic Stress Disorder (PTSD) - Year two

Urgent calls exist to address the mounting crisis of mental illness, and in particular posttraumatic stress disorder (PTSD), among public safety personnel (PSP; e.g., firefighters, police, paramedics) in Canada. Critically, PTSD is associated with alterations in cognitive functioning (e.g., poor memory and attention) that disrupt the ability of PSP to engage in activities such as work and family life. To date, however, no evidence-based treatment intervention exists to address cognitive dysfunction among PSP with PTSD.

Leveraging machine learning to improve trauma-related health outcomes

Severe and multiple traumas can lead to post-traumatic stress disorder (PTSD) which causes distress and difficulty in many areas of life. Military members, veterans, and public safety personnel such as police officers, firefighters, and rescue workers are often exposed to traumatic events on-the-job (seeing natural disasters, human violence, or death). One severe subtype of PTSD is PTSD with dissociation, where the person feels as if one’s body is not their own, or as if the outside world is not real.

The Efficacy of Goal Management Training for Cognitive Remediation among Public Safety Personnel with Post-Traumatic Stress Disorder

Urgent calls exist to address the mounting crisis of mental illness, and, in particular, post-traumatic stress disorder (PTSD), among public safety personnel (PSP) within Canada. PSP, including firefighters, police, paramedics, correctional services workers, Royal Canadian Mounted Police, operators and dispatchers, border services officers, and members of the Canadian Security Intelligence Service, are responsible for maintaining the safety and security of individuals, often placing themselves at risk by doing so.

Regulating Abnormal Connectivity in Posttraumatic Stress Disorder via Real-time fMRI Neurofeedback - Year two

Patients with posttraumatic stress disorder (PTSD) are characterized by decreased prefrontal cortex (PFC) regulation on hyperactive emotion generation regions, such as the amygdala. Real-time (rt)-fMRI neurofeedback allows for localized brain regions to be self-regulated through neuroimaging signal feedback. Recently within our lab, learning to decrease amygdala activation via neurofeedback was shown to normalize the neural circuitry maintaining PTSD, which was negatively correlated to symptoms.

Regulating Abnormal Connectivity in Posttraumatic Stress Disorder via Real-time fMRI Neurofeedback

Patients with posttraumatic stress disorder (PTSD) are characterized by decreased prefrontal cortex (PFC) regulation on hyperactive emotion generation regions, such as the amygdala. Real-time (rt)-fMRI neurofeedback allows for localized brain regions to be self-regulated through neuroimaging signal feedback. Recently within our lab, learning to decrease amygdala activation via neurofeedback was shown to normalize the neural circuitry maintaining PTSD, which was negatively correlated to symptoms.

Management of posttraumatic stress disorder: a multiple treatment comparison meta-analysis of randomized controlled trials

Traumatic events such as work related accidents, injuries or assault may result in the development of post-traumatic stress disorder (PTSD). This condition is associated with sleep disruption, nightmares, anxiety, and avoidance of the environment where the traumatic event occurred. Significant proportions of patients diagnosed with PTSD are disabled from working; however, little is known regarding which treatments are most effective for improving functional recovery. Existing research mainly focuses on the effect of treatment for reducing symptoms, and looks at treatments in isolation (e.g.

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