Portable COVID-19 diagnostic system using saliva sample

This project aims to develop an easy-to-use and cost-effective saliva test, fitted for COVID-19 diagnosis and
surveillance via multiplexed detection of SARS-CoV-2 viruses, COVID-19 specific antibodies immunoglobulin M and immunoglobulin G within 15 minutes.

Portable diagnostic device for outpatient BNP detection - Year two

Heart Failure (HF) occurs when the heart becomes damaged or weakened. HF is an epidemic, with approximately 1 million Canadians affected. BNP is an effective diagnostic and prognostic marker for HF. There is a direct correlation between elevated concentrations of BNP in the blood and the severity of HF symptoms. The need for point-of-care monitoring of BNP levels in the outpatient setting is imperative. The main objective is to develop a portable immunoassay-based electrochemical sensor for rapid detection and monitoring of BNP levels in outpatientÂ’s blood, for early detection of HF.

Portable diagnostic device for outpatient BNP detection

Brain natriuretic peptide (BNP) is an established prognostic marker for the early detection of heart failure. Elevated blood BNP levels are directly correlated to the severity of HF and decompensation. Current FDA approved immunoassays for BNP detection can only be carried out in medical laboratories or emergency rooms. Outpatient-use BNP monitors are yet to be developed. The objective of this project is to develop a prototype of the portable diagnostic device that can give a rapid electrical readout of BNP levels in a drop of blood.