Towards Fully Automated Tumor and Organ-at-Risk Detection and Segmentation from PSMA PET and SPECT Scans of Prostate Cancer Patients

Prostate cancer is the third deadliest cancer in men and early detection is crucial. PSMA is a protein that is highly present in prostate cells, making it a promising target for imaging and treatment. Total metabolic tumor volume (TMTV) is a measure of tumors' characteristics, but it is currently not measured in clinical settings due to the labor-intensive and time-consuming process of manually delineating the borders of all tumors in PET images. AI can automate this process, but it struggles with low-quality images and small tumors.

Simulating the Use of Agriculture as a Nature-Based Carbon Capture Solution for Mitigating Climate Change

Unmitigated climate change is expected to have catastrophic impacts on our way of life, causing governments and corporations to step in to pledge to reduce our emissions. However, to prevent warming beyond 2°C above pre-industrial levels, emissions reductions will likely not be enough, so we will need to take carbon dioxide directly out of the atmosphere, such as through planting more forests or changing how we do agriculture.

Clarifying Questions for Conversational Agents

Many conversational agents blend the functionalities of question-answering and chit-chat into a single system. This lays the foundation for a more interactive type of question-answering models which is the primary focus of the research project. Interaction between a user and the agent allows the user to ask an underdefined or ambiguous question, and, instead of the system returning its best response, the system is able to ask clarifying questions to help it hone in on an answer it can be more confident in.

Discovery and validation of SARS-CoV-2 epitopes

The global challenge for COVID-19 is to create a vaccine. A key step in the development of a subunit vaccine is the identification of the parts of viral proteins (epitopes) that will trigger immune protection against the SARS-CoV-2 virus. The purpose of this work is two-fold: 1) On the computer, we will develop and test the functionality of a new algorithm for selecting optimal epitopes for vaccine construction and for creating a diagnostic assay; 2) In the lab, we will identify SARS-CoV-2 peptides directly from cells infected with the virus or challenged with viral proteins.

Development of AI-enabled Tools for Advanced Clinical PET/CT Imaging of Cancer Patients

Over 200,000 new cancer cases are diagnosed in Canada each year. With imaging using an appropriate modality, many types of cancer that manifest as solid tumors can be detected, treated or managed effectively. Positron emission tomography (PET) combined with computed tomography (CT) is the primary imaging modality in a range of cancer types. Scientific studies have determined that measuring the size, shape, and texture of tumors from PET/CT images can help identify patients at high risk of early cancer recurrence, or for whom the standard treatment may fail.

An Integrated Interface for a Mixed Reality Based Medical Education System

How to build a medical education ecosystem and improve the learning outcome? Currently a medical education system based on mixed reality is missing and bad user interfaces can leave students confused and struggling instead of learning efficiently. The goal of this project is to leverage mixed reality technology, develop a medical education system, and make it easy to use.

Dance Like the Machine’s Watching

We are proposing an investigation of techniques and technologies to support media-enhanced group performances that integrate different performative art forms (dance, theatre, clown, voice, choral) with responsive mixed reality technologies and public data sets. We will work with a group of young performers (13-17 years old) and a local Vancouver choreographer to deeply investigate, with embodied methods, the potential ways of creating a group performance that truly benefits from a layered digital reality.

Advanced Data Science Research for Social Good II

Municipal governments and urban centres across Canada are being inundated with data—data that have potential to improve public service. Despite this, local governments do not have enough data expertise to extract insight from these overwhelming datasets. Simultaneously, high-quality personnel (HQP) in the domains of data science and urban analytics lack opportunities to work closely with local government to address this gap.

Analysis and Integration of Real-Time Mobility Data for the Cascadia Corridor

In order to design and operate more efficient urban transport infrastructure networks along the Cascadia Corridor, improved spatial and temporal data is required to understand travel activity patterns.

Investigating How Teachers Learn and Customize Digital Classroom Tools II

Our proposed research investigates how K-12 teachers learn and customize digital classroom tools and learning management systems and how they share this information with each other. In particular, we will be working with our partner Microsoft to investigate the use and customization of the recently developed OneNote Class Notebooks software that is increasingly being used by teachers for various content delivery and content management tasks.