Ultrasound-driven “on-demand” pulsatile delivery of chemotherapeutics or chemotherapeutic delivery vehicles to tumours

In many drug delivery methods, chemotherapeutic drugs have a hard time solely attacking cancer cells in a tumour and instead also attack healthy cells in the body, leading to severe side effects. Pharmasonica has developed ultrasound-responsive microcapsules that can be injected in the stationary tumour. These microcapsules have small silica nanoparticles on their outer shell that eject out upon ultrasound activation (similar to popping a cork on a wine bottle) to enable “on demand” drug release; the more nanoparticles ejected out, the more drug is released.