A pragmatic randomized controlled trial of a CKD specific telemonitoring platform to minimize adverse outcomes in high risk CKD patients

Advanced chronic kidney disease (CKD) patients require close surveillance, as CKD patients are at high risk of adverse events including death, acute dialysis initiation, emergency department (ED) visits and hospitalizations. Previous data from our population-based provincial study showed that there is a 10-fold increase in ED visits and hospitalizations related to kidney failure and its complications during the 30-day period before the start of dialysis.

Reducing dietary acid with fruits and vegetables vs. oral alkali in people with chronic kidney disease (ReDACKD)

This project involves a feasibility trial that is looking at fruit and vegetable delivery as a treatment for metabolic acidosis

Resistant Starch Prebiotic Effects in Chronic Kidney Disease (ReSPECKD) study - Year two

Chronic Kidney Disease (CKD) is associated with a reduced quality of life and an increased risk of kidney failure, cardiovascular events, and all-cause mortality. The goal of this project is to investigate whether the consumption of resistant potato starch (RPS) in addition to current standard care for CKD will reduce uremic toxins and symptoms by altering gut microbiota in patients with CKD. Strategies to reduce the production of these toxins by the gut microbiome in patients with CKD are highly desirable because they may lead to reduced symptoms and delay the onset of dialysis.

The Epidemiology of Fabry Disease and Metabolic Acidosis in Manitoba - Year Two

The proposed project is for the postdoctoral fellow to access healthcare data for individual adults in the province of Manitoba in order to: 1) determine the rates of metabolic acidosis in Manitoba along with associated outcomes and risk factor profiles and 2) identify patients in Manitoba who are at high risk of Fabry disease but currently undiagnosed in order to facilitate disease screening and improve patient care.

Resistant Starch Prebiotic Effects in Chronic Kidney Disease (ReSPECKD) study

Chronic Kidney Disease (CKD) is associated with a reduced quality of life and an increased risk of kidney failure, cardiovascular events, and all-cause mortality. The goal of this project is to investigate whether the consumption of resistant potato starch (RPS) in addition to current standard care for CKD will reduce uremic toxins and symptoms by altering gut microbiota in patients with CKD. Strategies to reduce the production of these toxins by the gut microbiome in patients with CKD are highly desirable because they may lead to reduced symptoms and delay the onset of dialysis.

The Epidemiology of Fabry Disease and Metabolic Acidosis in Manitoba

The proposed project is for the postdoctoral fellow to access healthcare data for individual adults in the province of Manitoba in order to: 1) determine the rates of metabolic acidosis in Manitoba along with associated outcomes and risk factor profiles and 2) identify patients in Manitoba who are at high risk of Fabry disease but currently undiagnosed in order to facilitate disease screening and improve patient care.

Evaluation of the clinically management weight-loss program at Wellness Institute at Seven Oaks Hospital

Many Canadians are overweight or obese which increases their risk for various diseases. However, many weight loss approaches don’t work. The objective of this project is to evaluate a weight loss program managed by doctors, dietitians and exercise specialists that focuses on improving healthy eating habits and increasing physical activity at the Wellness Institute. The Wellness Institute is a state-of-the-art certified medical fitness facility dedicated to improving the health of the community through health promotion and disease prevention.

Improvement of Operation Efficiency in WRHA Hemodialysis Units Using Simulation Modeling

Hemodialysis (HD) Units are the ambulatory care clinic for patients with the chronic kidney disease. There are 136 beds/chairs for over 400 patients per day at 3 HD facilities in Winnipeg. Inefficient workflows were identified from the previous study. This research will search solutions using methods of the system modeling and simulation to identify areas of improvement for the renal program workflows. Simulation modeling will be used as a cost-effective tool to examine HD operations, identify barriers to workflows, and test alternative solutions.