Development and preclinical evaluation of R-Sulforaphane-based therapeutics in treatment of chronic kidney disease

R-Sulforaphane (R-SFN) is a naturally occurring phytochemical that can be found in most of cruciferous vegetables, such as broccoli and kale. R-SFN has been shown in many research studies holding therapeutic promise for many chronic diseases. We propose to develop more advanced methodologies to product, purify and formulate R-SFN. We also propose to evaluate the therapeutic effect and safety profile of R-SFN in treating chronic kidney disease (CKD) in a rat model. If successful, the new developed product will benefit millions of patients who are suffering CKD by extending their life span and improving their life quality.

Jian Gao
Faculty Supervisor: 
Caigan Du
British Columbia
Partner University: