Development of Drug-eluting Bio-absorbable Scaffolds for Body Piercing Applications
Nearly 20% of all piercings lead to local infection, and therefore, it is imperative to develop alternative and commercially-viable methods of piercing aftercare to prevent infection. The general objective of the proposed project is to optimize the design of drug-eluting bio-absorbable scaffolds for human and animal tissue piercing applications with a focus on scaffold degradation and drug release properties. Methods of low temperature fabrication of drug-eluting bio-absorbable scaffolds will be developed and optimized. Moreover, the required scaffold geometry and concentration of drugs to be embedded within the scaffold will be determined based on the drug release profile and degradation rate (in-vitro).