EVALUATION OF THERAPEUTIC NATURAL KILLER CELLS
The intern will undertake the development and evaluation of a novel gene-edited immune cell therapy for the treatment of different cancer types. The cancer immune cell therapy is a hot and rapidly growing field that has yielded success and clinically meaningful benefits for the treatment of certain cancers. Many of these successes have been with a kind of treatment called CAR T cells, which are potent anticancer cell therapies yet pose significant safety concerns, namely a potentially lethal inflammatory condition called cytokine release syndrome and neurological complications.
Ankarys is a Canadian early stage start-up that is leveraging advances in gene editing technology and stem cell biology along with its scientists’ deep expertise in the investigation of cell therapies to develop a proprietary cell therapy product: engineered stem cell-derived natural killer cells. Natural killer cells are our body’s first line of defense against viral infections and cancer growth, and have been shown to be safe in different contexts of treating cancer.