One of the most significant screws emerged to connect timber members is the self-tapping wood screw (STS). This screw has primarily been developed to reinforce some of the weakest strength properties of wood. To further extent the application possibility of STS in timber construction, future research needs to address the potential of such screws not just as reinforcement but as connector between timber members. If self-tapping screws can be applied as a connector in timber construction at desirable cost and safety, this fastener will further help the timber industry penetrate into building sectors where performance is of prime importance. This would include the low-rise commercial, industrial and also residential building market all over North America and Europe. The proposed experimental research will establish a much needed database for STS connections under simulated earthquake loads. The proposed literature summary will highlight and clarify European design methods for STS to North American Engineers. The combination of both parts will allow practicing engineers in North America to apply this screw not just as reinforcement but as connector between timber members in large timber structures.