Multiplexing detection of infectious diseases biomarkers using fluorescence-encoded microspheres

Infectious diseases from a variety of pathogens can lead to serious health conditions such as sepsis. To improve the prognosis and decrease the mortality rate of infectious diseases, point-of-care testing (POCT) of blood biomarkers is a critical approach. Testing of biomarkers such as C-reactive protein, IL-6 and procalcitonin could help identify the type of pathogen and classify the progression stage of infection. This project focuses on developing microsphere-suspension based detection technology, combining with fluorescence detection device for the quantitative measurement of infectious disease biomarkers. This research project holds potential to provide healthcare access to people in remote areas, local communities and emergency rooms.

Intern: 
Xilong Yuan
Faculty Supervisor: 
James Stewart Aitchison
Province: 
Ontario
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