Neuroanatomical changes following chronic post-stroke therapy
Presently we do not know the extent to which different types of therapies can assist those who are in the chronic phase of stroke recovery. Technologically innovative rehabilitation devices are now becoming available to clinicians, and often employ video game-like scenarios to motivate the patient to move. However, there is a lack of evidence documenting a) the benefits of enhanced therapy using gaming-like devices, and b) the underlying neuroplastic changes promoted by the use of these devices. Here we will measure behavioural and neuroanatomical changes associated with an enhanced rehabilitation program (gaming-device plus standard therapy) in chronic upper-limb stroke patients. This study will provide important data concerning both the capacity for neuroplasticity in chronic stroke patients, and the effectiveness of enhanced, technology-assisted devices on functional recovery. The provision of evidence-based therapeutic practice represents important knowledge translation for thoseliving with disability brought about by stroke.