A Novel Bone Anabolic Treatment for critical size defects in rats

Often fractures don’t heal properly or large defects must be repaired in the bone due to accidents or disease. The drugs and treatments that are currently used to repair fractures are only partially effective. Mesentech Inc has developed a new drug that has shown a strong effect on bone formation in rats. In this project, we will test the effect of this drug in a rat model of normal healing and challenging healing. We will assess the effect of this drug, to accelerate normal healing and enhance challenging healing. We expect that the new drug will make the bones heal faster and better. This will open new treatment approaches to improve fracture healing.

Taylor DeVet;Jack Chapman;David Bertrand
Faculty Supervisor: 
Bettina Willie;Frank Rauch
Partner University: