Novel Serum Hormone Sampling Methodology: Applications for Understanding Ovarian Follicular Waves during the Human Menstrual Cycle

The menstrual cycle involves a complex chain of events between the brain, ovaries, and uterus. At the beginningof a woman’s cycle, the follicles (fluid-filled sacs in the ovaries that contain the eggs) grow, then one follicle isselected for further growth and eventually ruptures to release the egg during ovulation. Previous research fromour group has shown that follicles grow in 2-3 waves throughout the cycle. This study aims to use a new methodof collecting blood samples to evaluate how hormones from the brain and ovaries regulate the growth of folliclewaves in the ovaries. We expect that the knowledge gained will provide less painful and less expensive methodsfor collecting blood samples in men and women. We also expect that the results of this research will assist indeveloping new methods for hormonal birth control, fertility treatment and menopausal care. Results of theproposed research in women can be applied to develop similar blood sampling methods in the veterinary field.

Nike Bello
Faculty Supervisor: 
Angela Baerwald
Partner University: