Constrained Batch Estimation for Train Positioning with Inertial Sensors

Similar to current efforts in the automotive industry, there is a substantial interest in developing fully autonomous trains. One of the key steps towards enabling autonomous operation is being able to accurately estimate train position and speed. In addition to this, better estimates will also increase safety and reduce distance between trains, allowing more frequent trains in peak hours. The current project deals with a method of estimating the velocity and position without using GPS measurements, which is the standard method.

Preclinical development of monoclonal antibodies for the treatment of AL cardiac amyloidosis

Amyloid cardiomyopathy is an under-recognized cause of heart failure and is caused by normal proteins in the bloodstream going bad (known as amyloid) and accumulating in the heart. This accumulation of amyloid in the heart tissue causes the wall of the heart to become rigid and ineffective at pumping blood to the rest of the body, causing heart failure. We are studying a form of amyloid cardiomyopathy called immunoglobulin light chain (AL) amyloidosis, caused by the accumulation of light chain proteins.

Pollinator Steward Certification Program

The role of the intern will be assisting with the development, implementation, and evaluation of the Pollinator Steward Certification program in the Province of Ontario. In addition, research undertaken by the intern will seek to assess alignment of stewardship training with expected certification outcomes and current evidence of good practice as well as develop a ‘report card’ that brings together existing measures of socio-ecological well-being to assist conservationists and stewards to benchmark and assess their conservation efforts.

A data-driven framework for integrating visual inspection into injection moulding pipeline

Recent advances in machine vision has led to new opportunities for automating that entire manufacturing pipeline. Consider, for example, the situation where an unattended computer vision system inspects the widget and decides whether or not to discard it. Even this little amount of automation can save many hundreds of person-hours on a typical factory floor. While for simple designs, we now have automated inspection methods relying upon lasers, 3D scanning or other imaging modalities that can decide if a widget has any defect. For complex designs, this ability remains elusive.

Hydrogen Production From Utility-Scale Electrolysis for Fuel Cell Electric Bus Supply in Ontario

Hydrogen Fuel Cell technology is actively pursued as a viable, sustainable and long-term solution for resolving transportation-related emission issues on a global scale. While Canada has a strong presence in this technology space in various parts of the world such as Europe, the USA, and China, hydrogen technology integration at the transit level is still not a reality in this country.

3D Model-Integrated Automatic Change Detection

Earth is being imaged continuously using high-resolution (pixel-size

Next generation cannabinoids for chronic pain and opioid withdrawal syndrome – An alternative to opioid treatments and stemming the opioid crisis in Canada

The recent legalization of cannabis in Canada offers a unique opportunity to conduct fundamental research without the bureaucracy issues faced in other countries. The current state of cannabinoid-based therapies have focused their use in the treatment of cancer, pain, inflammation and opioid addiction, and suffer from unwanted side effects and lack of efficacy. Furthermore, the current opioid epidemic and the lack of better pain management strategies highlight the urgency for long-term solutions for chronic pain management.

Automotive detection of urban features from multi-scale imagery using Deep Learning

Mobility is an essential component of routine life for everyone. Walking and biking are two major transportation modes that help residents meet most or all of their daily needs. However, several mobility-related challenges occur as a result of weak maintenance of urban infrastructure such as sidewalks, bike lanes, and trails, which can decrease the safety of residents and may lead them to opt for vehicle-based transportation instead. One of the main reasons behind poor infrastructure maintenance is inefficiency of traditional inspection methods.

A Mobile Dual-Arm Robot for Autonomous Cooking Operation

The food services industry is ripe for a technological revolution. Challenging labor conditions such as rising minimum wage, high employee turnover, and scarcity of skills among other things makes it increasingly difficult for restaurants to be profitable and scale their business effectively. Delivering a quality product in a consistent manner with today's low-pay low-skilled workforce is difficult at best; and the hallmark of success in the food services industry is quality and consistency. Furthermore, there are sanitation risks in the interaction of workers and the food they prepare.

Enhancing exercise adherence in people with persistent musculoskeletal pain using a behaviour change approach

Persistent pain is pain that is prolonged beyond normal healing time, usually defined as three months. Approximately one in five Canadians suffer from persistent pain conditions such as low back pain, osteoarthritis and fibromyalgia. These conditions account for $43-60 billion in healthcare costs. Prescribed exercise has been shown to decrease pain while increasing function and quality of life, however over half of patients with persistent pain do not adhere to the exercises they have been prescribed.