Geomorphic sensitivity of rivers along the Niagara Escarpment to land-use and climate change: Implications for erosion risk in Hamilton, Ontario

The Niagara Escarpment is a dominant natural feature in southern Ontario and provides the region with exceptional sites of natural beauty including numerous waterfalls and exposed rocky cliffs. There is little data on geomorphic characteristics of rivers along the escarpment and their sensitivity to erosion under future land development and climate change. The proposed project aims to assess the sensitivity of rivers in the Hamilton area to erosion and its relationship to the underlying geologic structure of the Niagara Escarpment.

Data Analysis of Processing Infrasound Emissions from Maritime Vessels

Infrasonic signatures are long wave acoustic signals in the under 20 Hz range (below human hearing). The partner organization has been experimenting with infrasonic sensor systems to achieve 2 key outcomes: a) detection clear air turbulence to benefit commercial air travel and b) detection of marine vessels.The ability to detect clear air turbulence from the host aircraft in real time offers a savings to the airline industry (between $500M and $1B per year) in lost time accidents and costly fly arounds for suspected turbulence.

Development of cGMP-compliant manufacture of activated eCB-MSCs along with in vivo evaluation

Research into equine stem cells as regenerative medicine has been ongoing for over 20 years. Stem cell technologies hold promise for healing musculoskeletal tissues and wounds, fighting bacterial infections, and treating inflammatory conditions, but definitive evidence of the safety and therapeutic efficacy of these technologies have not yet been proven. A major limiting factor for conducting clinical trials to prove safety and efficacy is the lack of sufficient cell numbers with reproducible, standardized, and characterized properties.

Fabrication of an eye model using novel biomaterials and 3D printing

The use of sophisticated eye models can significantly reduce the costs of R&D for new eye products, while lessening the need to conduct animal testing. 3D bioprinting is a novel approach that would enable the design and fabrication of complex eye models. However, current 3D bioprinters are extremely expensive and not suitable for high-volume production. The aim of this study is to re-purpose commercial 3D printers for 3D bioprinting and develop compatible bioinks. This technology will then be used to create advanced eye models that includes all of the key structures of the eye.

Machine Learning for Non-Destructive Testing

IRISNDT deploys customized workflow productivity enhancement apps that are used by technicians in the field when performing Non-Destructive Testing (NDT) and mechanical work. This project will leverage expertise in AI at the University of Alberta to develop and deploy a suite of Data Science and Analytics tools to complement IRISNDT existing capabilities. The project will develop value-added capability that will contribute to IRISNDT maintaining its competitive edge and reputation as a leader in its field.

Automated Forensic Artifacts Collection Solution

Cyber attackers can sometimes compromise endpoint machines. They may perform malicious actions that will damage the company. As a result, it is necessary to collect forensics artifacts (Information from the endpoint machine that can be used to trace the attackers' behaviors) from the compromised machine for investigation. With the information we have, we may reconstruct malicious files, determine the goal of these attacks, or know how and when this attack happened. This project aims to automatically collect these forensics artifacts from endpoint machines and upload them to a secure portal.

Development of chemical property and process models for a new fermentation approach

Bioethanol is well-established as an alternative to petroleum-based fuels. A current roadblock in ethanol fermentation is end-product inhibition: where the increasing concentration of ethanol slows the growth of the yeast cells and their ability to ferment biomass. There is work being done to use existing separation technologies to remove ethanol throughout the reaction to avoid end-product inhibition, however these methods are often energy-intensive and therefore not feasible on a commercial scale.

A Novel Radiofrequency Treatment for Emphysema in Pig Model

A common condition that contributes to Chronic Obstructive Pulmonary Disease (COPD) is emphysema, which involves damage to the walls of air sacs in the lung. There are very limited safe and non-invasive options available, therefore IKOMED Technologies Inc. has been developing an application using radiofrequency wave technology that has shown the potential to non-surgically improve disease burden. The initial study was performed in the rodent model of emphysema with Dr. Don Sin, and study in larger animals is important for translation to clinical use.

Applying artificial intelligence to develop non-surgical treatment protocols for patients with adolescent idiopathic scoliosis

Adolescent Idiopathic Scoliosis (AIS) is a 3-dimensional structural spinal disorder that develops during the pre-pubertal growth spurt. There is a relatively short window for non-surgical treatments to be effective. Specific exercise and brace treatment are the most commonly used methods. Currently, there is no standard and no scientific protocol that can assist clinicians for an optimized non-surgical management of AIS.

Intelligent sensing devices for automatized non-invasive breath-based diagnosis

There is a permanent demand for technological advances in the automotive sector that allow the timely detection of drivers under the influence of alcohol. Although there are technologies to estimate alcohol in blood such as breathalyzers with a mouthpiece, the suspect individual needs to breathe through the mouthpiece as enough to reach the sensor threshold. This is inconvenient for people. Tools to reliably assess the state of sobriety of the individual behind the wheel and timely identify alcoholized ones are still missing.