Advanced technologies for breast imaging

The proposed Mitacs fellowship will provide a research opportunity for three post-doctoral fellows (PDFs) in a competitive R&D environment at the Thunder Bay Regional Health Research Institute (TBRHRI) – Canada’s newest health research institute. The research project is aimed towards the development and commercialization of the advanced radiation medical imaging detectors which will ultimately benefit healthcare in Canada and worldwide.

Hyperpolarized 129Xe Cerebral Perfusion MRI Imaging Development - Year two

Imaging of cerebral perfusion (the delivery of blood to a capillary bed in the brain tissue) is significant for diagnosing a variety of diseases. There are multiple challenges associated with perfusion imaging which significantly limits the quality of cerebral perfusion images. I am planning to develop a novel approach of cerebral perfusion magnetic resonance imaging (MRI) using hyperpolarized (HP) xenon-129 (129Xe). To conduct HP 129Xe perfusion imaging, I am developing a novel HP MRI Time-of-Flight (TOF) pulse sequence.

Development of a cost effective plant pathogen detection system with high specificity and sensitivity

Plant exposure to pathogen contamination can lead to serious health and economic risks. With the modern just-in-time logistics system, it is more critical than ever to have the ability to detect plant contamination to avoid the economic loss and health implications that can arise from plant contamination. Ecoli Sense is looking to develop a fast, inexpensive, and robust pathogen detection device for plant-based pathogens.

Optimizing High Performance Distributed Computing Framework in Heterogeneous Environment System at Lakehead University

Universities in Canada and around the world are adopting the DCP (Distributed Compute Protocol) as a method of obtaining free, abundant compute resources for research and innovation. In doing so, IT departments are deploying DCP workers on fleets of desktop computers in departments, libraries and administration offices on campuses. All of these computers, once connected to the distributed computer, consume network bandwidth, switching, and power resources. DCP is unique. Other utilities such as networks, cloud compute, and/or other mainframe systems have existed for years.

Hyperpolarized 129Xe Cerebral Perfusion MRI Imaging Development

Imaging of cerebral perfusion (the delivery of blood to a capillary bed in the brain tissue) is significant for diagnosing a variety of diseases. There are multiple challenges associated with perfusion imaging which significantly limits the quality of cerebral perfusion images. I am planning to develop a novel approach of cerebral perfusion magnetic resonance imaging (MRI) using hyperpolarized (HP) xenon-129 (129Xe). To conduct HP 129Xe perfusion imaging, I am developing a novel HP MRI Time-of-Flight (TOF) pulse sequence.

Low-Cost Sensor System for Remote COVID-19 Patient Monitoring

The rapidly increasing numbers of COVID-19 patients and long hospitalization periods place great strain on the current healthcare system in Canada. While some patients need hospitalization, most do not. To monitor those at home, accurate data is vital. There are several reasons that prevent continuous monitoring of the five physiological parameters (e.g., skin temperature, oxygen saturation, blood pressure, heart rate, respiration rate); most involve cost.

Catalysing Network Change: Exploring Practical Tools to Spark Food Network Action

Food systems organizations work brings together planners, community organizers, public health professionals, food producers, distributors and other food champions to transform food systems through direct action in communities, and collective action across organizations and regions. Many regions across Ontario have identified a fundamental challenge: moving from collaboration to action within their region.

Bullying Purposely Left Out?: Canada’s amended Labour Code and its potential impact on Indigenous workers

Workplace discrimination is common for Indigenous people (1,2). Unacceptable behaviours may take place at work, such as threats, intimidation, or violence (2). The workplace is a location where behaviour labeled as ‘bullying’ occurs (1,3). When examining Indigenous workers, the impacts of behaviour defined as bullying (and the mere act of defining the behaviour as bullying rather than racism, violence or harassment) may be exacerbated given the unique history of Indigenous people.

Development, implementation and validation of new anti-E6 therapeutics for the treatment of HPV-associated cancer - Year two

Human papillomaviruses (HPVs) are responsible for almost all cervical cancers. Current treatment available relies on chemo- or radiation-therapy or surgery. These methods have several side-effects with high morbidity and survival of just ~ 70%. Our lab, therefore, develops a more patient-centered approach based on targeting the viral E6 protein, the main culprit of carcinogenesis in HPV-related malignancies.

IoT-based Rental Item Location Tracking System

The purpose of this project is to add a feature to Rentrax so that business owners can track the physical location of their rental items. Device should be small enough to be hidden in rental items such as bikes. Battery usage of device should be as low as possible so that it doesn’t need frequent re-charge Location of device can be sent in real time or by receiving a signal or SMS and sending the location The fix and operating cost of device should be reasonable (fix cost below $30 and operating cost below $5 a month)

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