Optical fiber communications systems are used throughout the global communications network to transmit information over distances ranging from several kilometers to thousands of kilometers. This infrastructure is the backbone of the Internet that is used on a daily basis worldwide. Applications driving demand for increased capacity include (i) video streaming services, (ii) cloud based storage and services, and (iii) machine-to-machine applications.
In a full-duplex hands-free voice communication system, a speaker located in a room at one end of the link may receive an echo of his/her voice due to the acoustic coupling between the loudspeaker and the microphone at the other end of the link. The goal of acoustic echo cancellation (AEC) is to remove such undesirable echo to improve the quality and intelligibility of the voice communication.
Learning from relational data is crucial for modeling the processes found in many application domains ranging from computational biology to social networks. In this project, we propose to work on developing modeling techniques that combine the advantages of the approaches found in two fields of study: Machine Learning (through graph neural networks) and Statistical Learning (through statistical relational learning methods).
Water Rangers uses citizen science to acquire baseline data for water bodies across Canada by giving and selling testkits to volunteers across Canada. This project will explore who is most likely to take part in water testing, what engagement strategies reduce dropout rates, and how testing water increase environmental concern by changing values and people’s connection with nature. Using a mixed method approach involving surveys and interview questions, 275 participants will be recruited. They will receive a free tiny testkit, a subsidized mini testkit or borrow a large testkit.
A protein named c-Myc is causally implicated in over 50% of all human cancers. Preliminary work supports two proteins (POZ domain protein and c-Myc cofactor Miz-1) as a new drug target to disable c-Myc function. We have identified small molecules which act on this target and will now serve develop a series of optimized and effective molecules as cancer therapeutics.
To optimize these molecules, a combination of computational design and medicinal chemistry (synthesis and biological evaluation) will be carried out.
Steel rebars are the dominant reinforcement elements in reinforced concrete structures due to their relatively adequate manufacturing, material property and established construction codes. In an ideal environment and under nominal loading, conventional concrete reinforcement is expected to govern the design strength based on which they are designed. However, under environmental loading conditions, such as very low or very high temperature, deterioration of the steel reinforcement is accelerated and lead to significant structural, economic and environmental losses.
New studies have implicated the gut as the staging area for the start of Parkinson’s disease. Disruptions in the gut biota can promote the formation of toxic protein seeds that can move from the gut into the brain, spreading through the brain and causing progressive loss of neurons and problems with movement. It still needs to be proven if probiotics can help treat disease. We propose to examine this idea by testing how probiotics influence the function of neurons and other brain cells.
Who could have foreseen that humanitarian activities during the 2010 earthquake in Haiti would, 10 years later, guide the way for researchers, entrepreneurs and Mitacs interns during the COVID-19 crisis?
During his deployment at a Red Cross field hospital after the earthquake, Dr. Abdo Shabah saw the potential for greater use of technology in emergency health interventions.
As of July 27, 2020, the number of COVID-19 confirmed cases worldwide reached 16.3 million people, with 114,000 cases in Canada. About two to eight percent of COVID-19 cases experience severe symptoms that lead to respiratory distress, organ failure, and even death. Currently, regular medical checkups consist of one-on-one phone calls to monitor the patient’s vital signs remotely.