Developing niosome-based vehicles to deliver plant immune aids

Innovative approaches that ensure food security in light of the increasing world population, increasing variety of crop pests and microbes, and accelerating climate change are urgently needed. Suncor has developed a novel plant immune aid that can effectively enhance the disease resistance of crops to enhance agricultural yields. Through this collaboration with Dr.

Development of nano-colloid with gold nanoparticles to detect Legionella pneumophila using the principle of localized surface plasmon resonance

Legionnaires is a disease caused by the bacteria Legionella pneumophilia present mostly in aquatic environments. The first outbreak of this disease was recognized in 1976 in Philadelphia and the most recent one in July 2019 in Atlanta. Diagnosis of the disease isn’t early and thus need to be prevented by regular treatment. Treatment of water needs information about the water quality which needs on-site based sensors to detect the different pathogens present. At present, there is no viable solution to detect Legionella on site with confidence.

The Development of Novel Third Generation (3G) Advanced High Strength Steels Steels for Tank Car Applications

Railway tank cars are constructed from TC 128 steel plates, a design that has not changed for more than 50 years. The Lac Megantic rail disaster in 2013 refocused the attention of Canadians on the safety aspects of tank car design and operation, but not so much on the actual properties of the steels used to build them. In this project, we will explore the potential of modern advanced high strength steels as a replacement for TC 128. In particular, significant improvements to the tank wall puncture resistance will be targeted. New alloys will be designed using the latest scientific knowledge.

Characterization and Modeling Inclusion Population during Secondary Steelmaking - Year two

The ultimate goal of this project is to develop a fundamental understanding of inclusion evolution during a particular refining process in secondary steelmaking unit. The particular focus is firstly on developing a detailed characterization of the inclusions formed during refining in the Stelco Ladle Metallurgy Facility, and secondly on adapting the existing McMaster ladle metallurgy/inclusion model for the Stelco facility. Ultimately this is expected to achieve better process and product control. Inclusions, depending on their size and type, may profoundly affect steel properties.

Plant level implementation of a model for real time tracking and control of composition changes to steel, slag and inclusions during ladle processing – Part 2

The Ladle Metallurgy Furnace is used for adjustment of chemical composition and temperature, and control of tiny particles called “inclusions”. Controlling inclusions is carried out by adding calcium to modify the solid alumina or magnesium aluminate inclusions to less harmful liquid inclusions.
During ladle process, reaction of top slag, steel and inclusions occur simultaneously. Therefore, establishing a model to describe ladle process is indeed a challenge.

Objective Assessment of Suicide Ideation using Measures of Electrophysiology Data and Machine Learning

Digital Medical Experts Inc. (DME) is a Canadian start-up company in the business of developing cloud-based point-of-care monitoring systems for the management of psychiatric illnesses.

Accelerated detection and classification for surveillance applications

Object detection and classification for surveillance applications via deep neural networks have attracted a lot of interests in computer vision (CV) communities. Accurate and fast CV algorithms can alleviate intensive manual labour and reduce human errors due to fatigue and distraction. In detection problem, the aim is to determine bounding boxes which contain interested objects and classify the category of the detected object. Thus, the detection problem can be formulated as a regression problem to localize multiple objects within a frame.

Data-driven Assessment of Suicide Risk for Treatment Seeking Population

As part of this proposal the intern will be working with DME to develop and examine the viability of data-driven point-of-care system for the assessment of suicide risk. DME is a Canadian start-up company in the business of developing cloud-based point-of-care monitoring systems for the management of psychiatric illnesses. DME has developed algorithms to diagnose and predict optimal treatment for major depression disorder and schizophrenia, and has been allowed patents describing its technology in Canada, the USA, and Australia. If found acceptable the algorithms

Targeting platelet-neutrophil axis: a novel therapeutic approach for Scleroderma

Scleroderma or Systemic Sclerosis (SSc) is an autoimmune disease characterized by progressive fibrosis of skin and multiple internal organs and prominent and often severe alterations in the microvasculature. Although SSc is the third most common systemic inflammatory autoimmune disease, there is currently no effective disease-modifying therapy for SSc. The overall objective of this project is to develop a novel therapeutic approach for SSc via the modulation of autophagy levels in disease-causing neutrophils.

Behavioral Clustering in Big Data with Application in Super Customer Networks

Analyzing customer behavioral patterns and attrition aids organizations in understanding its core customers and improve its decision-making processes in regards to customer attrition and targeted marketing. In this research project, we will develop behavioural analytics super network models and algorithms for behavioural customer segmentation and attrition prediction in the presence of big data. Our models will help our partner organization develop better understanding of its customers and how to better manage their business relationships with them, thus solidifying its market position.