Neutral and alkaline bio-heap oxidation of refractory gold ores with adaptive moderate-thermophilic and mesophilic microorganisms

The project has been defined to address the growing concerns of the mining industry towards sustainable copper production with low cost and environmentally friendly process option. The current processes for copper extraction are either expensive or have detrimental impact on the environment. This proposed project pertains to the development of a technology that applied green energy (electricity) as well as ultrasonic technology to recover copper from the main copper minerals (chalcopyrite and enargite) with minimum cost and highest efficiency.

Advancing hip fracture recovery without complex technology

In this age group, around 50 percent of women and 25 percent of men will sustain at least one subsequent osteoporotic fracture in their remaining lifetime. After older adults sustain a hip fracture, decline in function and mobility can be rapid. The result is an increased dependency on care and financial burdens placed on their caregivers and the healthcare system. Up to half of hip fracture patients do not return to their pre-fracture functional levels and end up in long-term care institutions.

Development of a biosensor for high-throughput screening of novel ezrin inhibitors for treatment of metastatic breast cancer.

Treatment of metastatic breast cancer is often unsuccessful and lead to 5000 deaths in Canada each year. Therefore, there is an unmet need for new drugs for prevention and/or treatment of metastatic disease. Ezrin is a protein marker commonly over-expressed in metastatic breast cancer. Preclinical studies show that blocking ezrin can significantly reduce metastasis in breast cancer models. In this proposal, the intern will develop novel biosensors to screen large numbers of compounds with the ability to block ezrin’s activity in cancer cells.

The Social Ecology of Digital Archiving in Queer Arts Spaces

Like many LGBT+ (lesbian, gay, bisexual, transgender) community organizations, Reelout Arts Project Inc.
provides resources to people who experience social or geographic isolation – particularly through their
annual film festival and community film library. For these resources to reach broad audiences, however, they
must be able to connect with those who are searching for relevant material. The success of search results
has much to do with the organization of information online: the ways in which resources are described,
compiled, and presented to users.

Functional MRI investigation of the neural processes underlying pain modulation in human participants

Cannabis has been known to treat ailments for thousands of years, including conditions such as pain, cancer, arthritis, glaucoma, multiple sclerosis (MS) and amyotrophic lateral sclerosis (ALS). Despite an increase in research dedicated to molecular and behavioural effects of cannabinoids, there has been no direct evidence to elucidate the effect of cannabis on pain-related areas in the human central nervous system.

Toronto’s City Diplomacy: Arts, Culture, and Heritage

Our project, Toronto’s City Diplomacy: Arts, Culture, and Heritage, brings together scholars and practitioners in the cultural disciplines to consider how the Greater Toronto and Hamilton Area (GTHA) engages in cultural diplomacy and cultural networks locally and globally.

Development of compact enhanced nebulization systems for inductively coupled plasma spectrometry

The measurement of toxins, such as arsenic, mercury, cadmium, lead and chromium for example, in food, beverages, environmental samples, waters, etc. must be carried out to verify that there is no danger. This requires analyses of numerous samples each day using instruments that can measure the small amounts that may be present.

Improvement of inductively coupled plasma mass spectrometry for single particle and single cell analyses

The increasing use of engineered particulate matter in a variety of fields, including medicine, cosmetics and textiles, results in greater human exposure than in the past. As this matter may be swallowed or breathed in and penetrate the blood stream where it may reach organs and exert a toxic effect, techniques are needed that can quickly measure minute amounts of this matter in various media, such as the air that we breath, the water that we drink and the food that we eat.

Developing Recrystallization-Resistant AlScZrMn(Mg) sheets for automotive brazing applications

This internship project aims at developing superior alloy chemistries and processing routes for the manufacture of recrystallization-resistant AlScZrMn(Mg) sheets for automotive brazing applications. Various alloys will be thermodynamically modelled, cast and rolled to thin sheets followed by a stabilization heat treatment. The sheets will finally undergo a simulated heat cycle that resembles that of a typical brazing process during manufacture of automotive heat exchangers.

Creating a New Standard for Vision Loss Rehabilitation in Canada

Approximately nine million Canadians live with vision loss that, even when wearing corrective lenses, impedes their ability to perform everyday tasks. Canadians with vision loss are at greater risk of social isolation and reduced community participation. Vision loss rehabilitation (VLR) is a multi-disciplinary service that includes orientation and mobility training, independent living skills and low vision technology. These services are effective for improving the lives of people with vision loss. However, these services are varied and lack coordination in Canada.