Improving Social Justice and Economic Stewardship along the Global Value Chain: The Effectiveness of Interventions within Fragile Environments

Governments and consumers increasingly are demanding that companies take concrete action to improve environmental stewardship and social justice along their entire supply chain. In developing countries, however, this effort is hampered by lack of knowledge as to what kinds of initiatives yield positive outcomes. This research is a pilot project to develop new insights into the conditions under which local mining communities can improve their living conditions.

Understanding the Evolving Nature of Refugee sponsors in Canada

This project examines the type of refugee sponsorship groups, their relation to the sponsored refugees, and the challenges and successes that they have faced. This is primary research, using the data that is at this point available but not organised by the partnership organization. It will benefit the partnership organization in giving it an overall, empirically valid assessment of areas of improvement in public policies that are adapted to changing circumstances.

Economic impact and feasibility analysis of public investments in broadband connectivity, and in other sectors

Interns will perform research leading to the design or the implementation of new economic strategies that can be utilized in the design, financing, monitoring and evaluation of projects at different stages. Specifically, interns will work on an analysis of equitable access to broadband connectivity in Kingston, ON, as part of the City’s plan to expand broadband access. By analyzing the benefits of broadband access and where gaps currently exist, the research will result in policy recommendations.

Investigating polysaccharide-protein conjugation: characterization and effects of glycation conditions

Pneumonia remains the single leading cause of childhood death under age 5 worldwide. The price per dose of current vaccines is high and supply is limited due to a complex manufacturing process and low yield, significantly reducing its distribution in developing nations.1 A newly patented vacuo dry-glycation process promises much higher efficacy than the conjugation chemistry used currently, paving the way towards a much lower dosage cost. and its vaccine is a kind of polysaccharide-protein conjugate system.

Advanced Characterization of Zirconium Hydrides in Zr-2.5Nb Pressure Tube in CANDU Reactors

In the operation of CANDU reactors, the Zr-2.5Nb pressure tubes holding the cooling water and fuel bundles are susceptible to hydride cracking-induced crack initiation mechanisms, known as delayed hydride cracking and overload crack initiation. For structural integrity evaluation of CANDU pressure tubes, of fracture toughness and hydride crack initiation models were developed. However, the hydride morphology input for the model is still based on microstructures taken decades ago.

Geophysical Prospecting for Antimony (and Chromite) in the Southern Quesnel Terrane, British Columbia, Canada

Antimony is classified as a strategic element due to its high relevance for many military and technical applications, e.g. its use in fire suppressants and lead-acid batteries. Canada has currently no operational mine to produce antimony and about 90% of the world production originates from China and east Asia. This project will develop a geophysical prospecting program to explore for antimony, which has been discovered in samples taken from the industry partner’s mineral claim in the southern Quesnel terrane, northwest of Kelowna, British Columbia.

Financial and Economic Analysis for the Integration of Wind Generation into Electricity Grids

This research effort will measure the impacts that the introduction of wind farms have had on the amount of electricity generated by natural gas fired thermal plants, hydro generation, nuclear generation or the quantities of electricity exported. For this analysis the historical operating information from the Province of Ontario’s electricity system will be used. An ex-post evaluation will be carried out for one or more wind farms operating in Ontario to identify the important parameters that determine the economic feasibility of such investments.

Neutral and alkaline bio-heap oxidation of refractory gold ores with adaptive moderate-thermophilic and mesophilic microorganisms

The project has been defined to address the growing concerns of the mining industry towards sustainable copper production with low cost and environmentally friendly process option. The current processes for copper extraction are either expensive or have detrimental impact on the environment. This proposed project pertains to the development of a technology that applied green energy (electricity) as well as ultrasonic technology to recover copper from the main copper minerals (chalcopyrite and enargite) with minimum cost and highest efficiency.

Advancing hip fracture recovery without complex technology

In this age group, around 50 percent of women and 25 percent of men will sustain at least one subsequent osteoporotic fracture in their remaining lifetime. After older adults sustain a hip fracture, decline in function and mobility can be rapid. The result is an increased dependency on care and financial burdens placed on their caregivers and the healthcare system. Up to half of hip fracture patients do not return to their pre-fracture functional levels and end up in long-term care institutions.

Development of a biosensor for high-throughput screening of novel ezrin inhibitors for treatment of metastatic breast cancer.

Treatment of metastatic breast cancer is often unsuccessful and lead to 5000 deaths in Canada each year. Therefore, there is an unmet need for new drugs for prevention and/or treatment of metastatic disease. Ezrin is a protein marker commonly over-expressed in metastatic breast cancer. Preclinical studies show that blocking ezrin can significantly reduce metastasis in breast cancer models. In this proposal, the intern will develop novel biosensors to screen large numbers of compounds with the ability to block ezrin’s activity in cancer cells.

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