British Columbia__University of British Columbia

No additional funding contribution is required from the academic supervisor or university.
Fellowships will be awarded competitively.

Preliminary Investigation of Innovative Processes to Recover Nickel from the Decar Deposit

The Decar nickel deposit is located in British Columbia. With more than 2 billion tons of reserves grading 0.2% Ni the deposit represents a significant resources. The nickel occurs in an uncommon mineral awaruite which is an alloy of nickel and iron. Due to its strong ferro-magnetic properties and high density (SG 8.0) it should be readily recoverable using magnetic separation followed by gravity concentration. However, the presence of significant amounts of magnetite which as similar physical properties makes it difficult to separate the awaruite from the magnetite.

Testing, evaluation and development of a commercial protocol to differentiate hPSC-derived pancreatic progenitors into insulin-producing ?-cells in 2D monolayers and/or 3D culture systems

The generation of functional ?-cells from human pluripotent stem cells (hPSCs) for cell replacement therapy and disease modeling of diabetes is a strongly investigated area. Recent scientific breakthroughs have enabled derivation of large quantities of human pancreatic ?-like cells in the laboratory, but the protocols are currently not consistent or optimized for cells of various genetic backgrounds. We aim to develop a commercial kit to differentiate hPSCs into ?-cells with reproducible efficiencies between multiple cell lines.

Evaluation of interventions for improving maternal, newborn, and child health outcomes: Systematic literature reviews and network meta-analyses

Poor nutrition, sanitation and hygiene, and infectious diseases during pregnancy and early childhood can lead to poor growth and development that can be everlasting negative effects on the child. A large number of clinical trials have been conducted, but as many interventions have not been compared against each other, it is unclear what interventions are effective and should be provided over different life stages of the child.

Development and characterization of nano-emulsification and liposomal platforms (NEP and LIP) for hemp oil nanoencapsulation and transmucosal delivery

A novel technology for delivery of biologically active compounds found in hemp oil is being developed. This novel technology significantly reduces the health risks associated with traditional administration of Cannabis products (e.g., smoking and THC-related intoxication) The proposed project, in collaboration with a federally-licensed facility for cannabinoid analysis, Abattis Bioceuticals, engages into the development of two different platforms for encapsulation of hemp oil using nanoemulsion and nanolipid carrier technologies.

Machine learning methods for signal classification in anti-drone technology

Drone technology has recently gained wide-scale acceptance in multiple military and commercial applications, including security surveillance and medicine delivery. In 2017 alone, the market revenue from drones is estimated to be around $6 billion. With this, there is also an emerging need for sophisticated anti-drone technology to detect rogue drones entering secure territories, such as military bases and prisons.

Visualizing data for Fraser River salmon stocks: Developing tools to promote insight and understanding

For this project, we propose to integrate the data about Fraser River salmon populations into a multi-species, multi-population database, and develop an interactive data visualization tool that allows fisheries scientists and managers to explore this data at different spatial and temporal scales. The objective of this project is to provide fisheries scientists and managers with the tools to easily and comprehensively track annual trends in salmon data, and explore these trends for their possible drivers.

Development of new therapeutics for castration-resistant prostate cancer treatment

Castration-resistant prostate cancer is a late stage disease and many people die of it due to lack of effective therapeutic drugs. In the current project, we propose to develop new therapeutic drug a to specifically target CRPC’s common weak points, which are MCT4 and eIF4E gene’s proteint products that play very important roles in regulation of cancer cell’s energetic and protein translation pathways. The project aims to develop an antibody drug, an small molecule chemical drug and a nanoparticle drug to target MCT4 membrane protein and eIF4E transcription factor protein.

Green Chemistry for Green Solvents

A major contributor to smog formation is the release of volatile chemicals into the atmosphere which are emitted from many sources including automobile exhaust and consumer products such as paints. To combat the adverse effects smog has on air quality in North America, agencies such as Environment and Climate Change (Canada) and the Environmental Protection Agency (United States) enforce limits on the types and amounts of chemicals used in industrial applications and consumer products.

Celebrating 1,500 interns in 2018 and 20 years together

Mitacs internships facilitate connections between university students and non-academic partners across Canada. Partner organizations get the immense benefit of high-quality, rigorous research support and access to ground-breaking knowledge from academia—which may be inaccessible otherwise. Highly-skilled students get to apply their research expertise beyond their academic settings, while also building important skills and connections that serve them after graduation.

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