Species-at-risk conservation is complex and multi-faceted. However, mitigation strategies are typically narrow in scope, an artefact of conservation research that is often limited to a single species or stressor. The ability to research an entire community of strongly interacting species would greatly enhance our ability to forge more comprehensive and effective conservation decisions. Seismic line restoration is a key management strategy for caribou conservation but little is known about the response of this restoration on boreal mammals generally, or caribou, specifically.
Proteinuric kidney diseases, such as lupus nephritis, affect approximately 1 in 10 individuals around the world. For many patients, it results in the progression to end-stage kidney disease, for which the only treatments available are dialysis and transplantation. Therefore, it is imperative to develop therapies that slow down or halt the progression of proteinuric kidney disease. Voclosporin (VCS) is a next-generation calcineurin inhibitor currently in phase 3 clinical trials. It confers increased potency when compared to other drugs currently used to treat proteinuric kidney disease.
To sustain its leadership in the world marketplace, the Canadian pulp industry must continue to increase pulp quality, while it improves manufacturing efficiency, reduces energy consumption and decreases impact on the environment. Properties of a manufactured pulp vary with production parameters and characteristics of the feedstock. To produce pulps of the highest quality at lowest cost, a manufacturing process must continually optimize its conditions to fit the feedstock.
This project investigates a new perspective on the intersections of architectural form generation, sustainability, building performance simulation and computation, and is meant to research an energy performance-driven building space organization method in the preliminary design phase.
It will enquiry clear design questions, and present results using a visualization method that addresses the problem for both architect and engineer. Accompanying with computer algorithmic form generation, it will facilitate the designers with more solutions scientifically, efficiently and economically.
Recent severe forest fire activity and loss of vegetation from Mountain Pine Beetle has resulted in impacts to river channel stability and Chinook salmon habitat in several key sub-catchments of the Thompson River Watershed. Interest exists in conducting remedial work to improve and restore salmon habitat in several locations, but risk of ongoing channel instability from forest cover change continues.
Salmon are inarguably one of the most culturally, ecologically, and economically important fish in British Columbia, however, their stocks have been declining since the 1990s. The Cohen Commission of Enquiry expert panel emphasized that juvenile mortality during the first months at sea was the most likely cause of fishery declines. This Mitacs project represents Phase 2 of a research initiative addressing the role of ocean conditions in the early marine survival of juvenile salmon.
Chronic obstructive pulmonary disease (COPD) is an inflammatory disorder of the lung, and one that affects 2.6 million Canadians and 380 million people worldwide. Although the disease affects a large population worldwide the therapies used for treatment remain imprecise. With the lack of disease modifying therapies there is a pressing need to discover novel targets to promote new therapeutic discoveries and ultimately improve the care and health outcomes of patients with COPD.
Sustained operation of sanitary pumping stations in Richmond BC is critical to the health and safety of its residents. The overarching goal of this research project is to investigate strategies to improve urban resilience by operating the sanitary pumping station loads in coordination with distributed energy resources (DERs), including renewable generation and energy storage. Particularly, this project aims to develop a decision-making tool to optimize infrastructure investment in DERs while promoting resilience of sanitary pumping stations.
Thousands of kilometers sewage pipelines suffer from severe bio-corrosion caused by prolonged exposure to highly aggressive environments. Over the past several decades, many approaches have been developed to reduce the risk of concrete bio-corrosion with variable degrees of success. Over the last 6 years at UBC, a novel cement-free corrosion-resistant coating material was developed to enhance pipes durability and service-life. The proposed project aims to develop sprayable MCC coating for repair and strengthening of corroded wastewater pipes.
The project aims to refine a process developed by Terra CO2 Technologies to use a small proportion of geopolymer cement made from mine tailings to solidify and stabilize a bulk volume of tailings against leaching and water contamination.