Frontiers in Continuous Variable Quantum Computation: From Theory to Practical Demonstration

Continuous variable (CV) encodings in photonic systems are emerging as one of the most promising avenues to near term, practical, quantum computing. In order for a CV quantum computer to outperform its classical counterparts it requires the integration of at least one “non-Gaussian” element.

Hybrid and multi-device quantum machine learning models

Over the past 2-3 years, commercial quantum computing hardware has begun to come online. While emerging quantum processing devices (QPUs) are still small and noisy compared to ideal quantum hardware, they are nevertheless expected to demonstrate quantum supremacy soon. During the same period, quantum machine learning (QML) has emerged as a rapidly expanding research field, perceived as one of the most promising algorithmic paradigms for near-term quantum computers. In this project, the candidate will leverage their skills in machine learning to carry out research in QML.

Understanding the Mechanism of Probiotics for Human Health

DoseBiome has developed a new probiotic that targets several aspects of oral health: dental caries, periodontal diseases, and halitosis. This project aims to understand the exact mechanism of our probiotic's inhibitory properties against the pathogens associated with the above diseases. DoseBiome is a new start-up in the probiotic/microbiome health sector, and this project will allow for improved technology and manufacturing processes for our oral probiotic line.

Investigating the effect of novel nutritional compounds on skeletal muscle protein synthesis and growth in vivo

Resistance exercise training combined with adequate post-exercise protein ingestion is known to increase muscle mass when completed repeatedly over a prolonged period of time (>6 weeks). Due to this knowledge much research has been conducted to identify the best protein supplements which allow for the greatest muscle growth with training.

Fabry-Perot Pressure Sensors for High Temperature Applications

The use of advanced manufacturing methods and analysis tools and bringing them to the plant floor is crucial for modern manufacturing. A gap that has become apparent is that often engineering capabilities are not available within many facilities – and this requires robust design and new thinking to ensure manufacturers ensure quality product. The pressure transducer is a device thathas not changed much over the past twenty year. This work will provide guidance through an improved pressure sensor for high-temperature applications by introducing optical approaches.

Recovery of rocky intertidal communities post-pollution disturbance

This project will aim to assess the impact of past pollution events from historic and ongoing anthropogenic activities in Coastal BC. This pollution has potentially led to a change in species presence at those sites. The intern will take part in field work activities, data analysis (including the assessment of species diversity) and reporting. Hemmera will use the results of this project to improve their understanding of coastal marine ecosystems and their responses to changes caused by human activities.

BTRC and FBXW11 Ligand Discovery Toward Discovery of E3 Ligase Handles

Drugs that inhibit a protein’s function do so by binding that protein and blocking interfaces relevant to its activity. This requires drugs to have high affinities towards and to be in high excess of their targets. Another approach called Proteolysis targeting chimeras (PROTACs) can be used, which hijacks a cell’s protein-degradation pathway by linking an E3-ligase to a target protein, leading to that protein’s degradation. To date, PROTACs molecules only utilize a handful of the over 600 potential E3 ligase handles and this limits PROTAC developmental potential.

Efficacy of Radiant Energy Veils in Multi-glazing Fenestration

Today buildings, which account for 40% of the total global energy consumption, constitute large glazing surfaces given that windows provide the necessary spacious feel and direct daylighting for occupants. However, 60% of the heat loss through its exterior surface is attributable to glazed surfaces (windows). Therefore, it is not surprising that advanced fenestration products have enormous potential to realize large energy savings and contribute toward the vision of net/near-zero energy buildings.

Treating the Untreatable: Targeting Paediatric Brain Tumours with Multi-omics and Drug Discovery - Year two

Brain tumours, including ependymoma, are some of the most difficult cancers to treat. Although the past few years have seen many exciting advances in characterizing these brain tumours, there are few effective therapies available for patients, many of whom are children and young adults (and for whom long-term side effects can be extremely damaging). Until very recently, research in this area has been hampered by a complete lack of cell lines and animal models.

Developing Cannabis resources for the 21st century

Over the past few years Cannabis has gone through a revolution with respect to its applications to both the medical and recreational markets. For legal reasons, much Cannabis genetics has been hap hazard but now with legalization scientific approaches can be used to develop useful Cannabis strains for the industry. In this proposal, we will develop two transformative programs to revolutionize Cannabis genetics. The first involves the development of a cheap fast method to identify Cannabis strains.