Evaluation of the remedial actions in the Toronto and Region Area of concern

The Toronto and Region Area of Concern (TRAOC) has been one of the most polluted sites in the Great Lakes posing health risks to millions of people. The Remedial Action Plan (RAP) has made significant progress towards restoring the system and meeting the delisting targets. Yet, several critical questions still need to be addressed, such as: How close is the Toronto ecosystem currently to meeting the TRAOC RAP delisting criteria? What additional research and assessment will be required to guide remedial actions? Which attributes best reflect the integrity and health of the ecosystem?

Using Electronic Health Records to Predict Key Patient Health and Organizational Outcomes

One of the proposed benefits of adopting electronic health records is the development of a comprehensive database which can be used for epidemiological, clinical, and health services research. The main purpose of this project is to develop strategies and provide case examples of how data from these extensive electronic databases can be used to improve healthcare services outcomes. TELUS Health Solutions’ Oacis (i.e., Open Architecture Clinical Information System) has been in use in a large health care organization for approximately 15 years.

Integrated Pulse Shaping Devices

Pulse shaping devices are the key elements for optical signal processing that are capable of reshaping the temporal waveform of optical pulses.  The applications of pulse shaping devices include ultrahigh-speed optical telecommunication, ultrafast all-optical computing and information processing, biomedical imaging, and electronic and photonic signal/device characterization and monitoring. For these applications, ultrafast optical waveform shapers capable of synthesizing temporal waveform features down to the sub-picosecond regime are required.

Heterojunction colloidal quantum dot based solar cells

Solar power is one of the most promising renewable energy sources and its terrestrial abundance is several orders of magnitude higher than world’s consumption. Conventional solar cells, however, collect only a portion of solar energy – mostly visible sunlight. Our technology is capable of collecting the entire solar energy spectrum by using semiconducting nanocrystals (NCs) as the photovoltaic material.

Eco-Friendly coatings and formulations for the wood industry

Ecoatra is applying new developments in nanotechnology to solve the long-standing problem of hazardous substance use in the wood industry- one of our oldest and largest industries. Ecoatra’s formulation uses nanotechnology to enable deeper and more uniform penetration into wood, versatile application,  increased performance and potency at lower material quantities translating to reduced costs, multifunctional properties including water repellence, antimicrobial properties, and protection from UV light

The travel behaviour of recent immigrants in the Greater Toronto Area

The proposed research will explore how diverse recent immigrant populations in the Greater Toronto Area (GTA) use the transportation system to meet their daily-life needs.  The objectives are to explore how these groups make use of surrounding urban environments, provide a description of the processes used to secure transportation and the barriers faced, and examine the differences in experience across various urban and suburban jurisdictions.  Certain findings will have implications for low-income households in gernal, and for other groups with limited driving ability.  The proposed projec

Identification of a molecular profile predictive of metformin sensitivity in human breast cancer.

Breast cancer (BC) accounts for 15% of all cancer cases in Ontario, affecting 8,700 women in 2009.  Thus, there is a great need for the development of new anti-cancer agents and the identification of patients who are best suited for tailored treatment.  The drug metformin has emerged as a potential therapy for BC.  Metformin is commonly used to treat type 2 diabetes, but clinical studies have demonstrated that it can inhibit BC.  However, it is unclear how metformin inhibits BC and which patients would be most suitable for metformin therapy.  Therefore, the goal of the project is to determi

Design of a novel magnetoencephalograph-compatible tracking system for monitoring speech-related orofacial events

Individuals with speech problems face difficulties such as anxiety, poor socialization and poor literacy. Key to effective intervention and therapy is a better understanding of the brain activity associated with speech. Magnetoencephalography (MEG) is a new brain-imaging technology that, for the first time, allows researchers to monitor the fast-changing brain activity involved with speech. The challenge in using MEG for speech analysis is that existing speech-tracking systems introduce too much magnetic interference.

Developing a prototype electrowetting on dielectric device to perform immunoassays

The goal of this project is to develop a prototype microfluidic device to rapidly determine whether a target protein is present in a sample. Applications of this device include genomic and proteomic research, pharmaceutical testing, and quality control for various industries, including food preparation. The prototype will make use of electrowetting on dielectric (EWOD) actuation, which uses the application of electric fields to manipulate confined droplets. Unlike conventional microfluidic devices, EWOD devices do not require complex features for flow control or external pumping.

Building Surfaces from Curve Sketches

In recent years 3D sketching has received considerable attention and a number of powerful tools (such as ILoveSketch) have been developed which can interpret strokes of a design artist as three-dimensional curves. Using these tools, the artist can create, in roughly the same time it takes him/her to draw a single 2D sketch, a loose 3D wireframe model of his/her intended object in the form of a collection of curves in space. In this project, we intend to intend to extract actual 3D surfaces from such collections of space curves, thus turning the end result into a true 3D model.

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