Many individuals acquire infections each year, yet few progress to critical illness. The current inability to identify the proportion of individuals who will progress to life-threatening illness is a major impediment to effective management of infectious disease. Using malaria as a model, the aim of the project is to identify and validate a panel of biomarkers in blood that reliably detects individuals at risk of lifethreatening disease.
The goal of the current research is to design an injectable polymer-lipid (Pol.i) formulation to treat ovarian cancer. The PoLi drug delivery system is a hiocompatible and biodegradable, physically cross-linked gel that has the potential to provide dramatic improvements in the treatment of ovarian cancer. It is formulated as an injectable gel (all components are safe for humans) which is then loaaded with active chemotherapy drugs such as the commercially available paclitaxel.
Ontario is investing $100 Million over 10 years in the process of updating the Provincial Forest Resource Inventory (FRI), which involves the province-wide acquisition of new digital ADS40 aerial imagery to serve as a consistent platform for the photo-interpretation and mapping of forest attributes.
This project explored the effectiveness of an educational technology called peerScholar, which is an online peer-assessment tool used to enhance student learning. To date, all of the findings on peerScholar have focused on the development of critical thinking skills at the University level. However, given that learning begins earlier, the proposed research will examine the effectiveness of peer-assessment, via peerScholar, throughout Grades 9 to 12. The goal Is to replicate, and to extend, the peer-assessment findings with younger students.
The proposal research concerns the creation of innovative tools to improve the quality and effectiveness of modeling in software development. Specifically, the research will focus on three areas: how to express the relationships between models to make sure that models are properly synchronized with each other; how to express different variations within the model so that the same model can be used to produce software for different situations and how to express the intent (purpose) of a model so that it can be more easily understood and checked to make sure that it correctly satisfies its pu
Information and communication technologies (ICTs) are poised to have increasingly larger roles in health care systems globally and one possible scenario is that Ontario emerges as a leader in providing eHealth innovation and service delivery. Although ICT-based methods of service delivery are well established in particular areas of health care, the potential benefits for hearing health care have not been fully realized due to a number of technological and non-technological barriers. Foremost among them, successful aural rehabilitation requires face-to-face consultations where practitioner
This project involves working with researchers at the Bloorview Kids Rehab in Toronto to aid them in developing safer and more advanced brain]computer machines for individuals with severe physical limitations. The intern is developing a computer-based visual analytics tool that will help them further interpret the data they are collecting about brain activity. This tool will enable them to identify and compare change points in the data which could not previously be identified; a necessary step to developing advanced brain]computer machines.
This project seeks to simplify the development and management of business processes deployed on a distributed Service Oriented Architecture (SOA). The target architecture is an enterprise system with distributed services coordinated by application workflows or business processes. Declarative goals, specified in Service Level Agreements (SLA), are used to assist in the development of such applications, and to automate the monitoring, deployment, and resource provisioning tasks.
In this internship, UNS-Tech will partner with Prof. Woolley to detect products of interest to his lab using UNS-e-chip. The antibiotics, developed by Prof. Woolley, are novel systems that can be activated by light or enzymes. The assay will employ UNS-Tech’s state-of-the-art electronics-based detectors for HPLC. The results will be analyzed and the findings will be published in scientific journals. The intern will benefit from this internship by gaining tremendous knowledge of synthesis of products of great value to the pharmaceutical industry.
Chinese cities are amongst the fasted growing cities in the world and they have per capita greenhouse gas (GHG) emission rates that are similar to western cities. This research quantifies GHG emissions for the three Chinese city]provinces of Beijing, Shanghai and Tianjin. A computer model is then developed for projecting the future growth in Shanghaifs emissions under current policies and infrastructure plans.