To reduce the impact on natural resources and extend the lifetime of existing quarries, this research will attempt to reduce the large quantities of quarried rock that are currently wasted for simply not meeting current aggregate grading requirements in standard construction specifications, even though some of those wasted size fractions would improve the quality and sustainability of concrete. By optimizing aggregate particle packing, more workable and durable concretes can be produced while also reducing the carbon dioxide producing, and energy-intensive, cement content.
Infrared spectroscopy is a fundamental technique to study novel materials ranging from medicine to semiconductor industry. Regular infrared sources can provide very limited spatial resolution for infrared microscopy experiments. Currently, this limitation can be overcome with the use of synchrotron sources. A recently discovered and now commercially available alternative light source is the Quantum Cascade Lasers (QCLs). Their limitation is that QCLs have a small range of tunability.
The aim of this grant proposal is to address the challenges with current CT Coronary Angiography (CTCA) utilization with a comprehensive series of interrelated but well-defined research themes. This non-invasive technique has facilitated in the detection of significant coronary artery disease and vulnerable plaque. However, the quality is limited to the physicality of the patients in particular to the population who are at the greatest risk of coronary arterial diseases (CAD).
The loss of bone is a massive burden on the health care system and severely impacts the quality of life of several hundred million people. The need for alternative strategies to replace or regenerate bone tissue is overwhelming. We are proposing a completely new approach to the engineering of bone using a ―cocktail‖ of genetically modified human umbilical cord perivascular cells (HUCPVCs) that can be produced in vast numbers, stored in liquid nitrogen so that they could be ready for therapeutic purposes.