As consumer preferences shift from shopping at brick and mortar stores to on-line shopping, there is an increased need for warehouses to use automated systems that fill orders quickly and accurately. This research project will design a warehouse robot that is adaptable to different platform systems and shelving configurations, providing a lighter, faster, and more cost-effective warehousing system.
Ideal flow, high-volume Powder Metallurgy (PM) manufacturing can achieve uniform, consistent filling of die cavities, leading to high productivity, low rejection rates, improved part integrity and consistent part dimensions. The type and amount of lubricant, size and shape of lubricant particles, mixing parameters and certain environmental conditions all significantly influence the flow characteristics and apparent density (AD) of powder mixtures.
Rechargeable aqueous zinc ion batteries (RAZBs) have been used extensively because of their safety and low-cost. As an available cathode material for ZIBs, layered vanadium oxide (V2O5) has been considered due to its high specific discharge capacity. Because V2O5 is slightly soluble in water, it is suitable for modifying V2O5 with conductive polymers to stabilize its crystalline structure and decrease the solubility of V2O5 in aqueous electrolyte systems. In-situ polymerization will be used to coat polymers on the V2O5 surface.
In commercial batteries, metal anode-based batteries, mainly using zinc or lithium as the anode, provide higher battery capacity than traditional metal ion batteries. Lithium metal anodes have a theoretical specific capacity 10 times higher than commercial lithium ion batteries with graphite as the anode. Zinc anodes are excellent anodes for use in aqueous batteries, because they offer the highest energy density of all aqueous battery systems and low cost.
This study aims to develop a scoring system to screen the sub-clinical forms of rotator cuff tears and predict the tear progression. All the medical, genetic, work, and lifestyle backgrounds of individuals with rotator cuff defects (with and without symptoms) will be evaluated and a battery of manual tests and measurements will be performed to understand the predisposing risk factors for both sub-clinical and clinical manifestations.
In this project, the main objective is developing a peptide-based environment sensitive siRNA delivery system for cancer treatment. If this deliver system can be proved efficient both in vitro and in vivo, it could have potential feasibility to be further characterized and become a pharmaceutical drug eventually.
As a result of recent advances in high-throughput technologies, rapidly increasing amounts of mass spectrometry (MS) data pose new opportunities as well as challenges to existing analysis methods. Novel computational approaches are needed to take advantage of latest breakthroughs in high-performance computing for the large-scale analysis of big data from MS-based proteomics. In this project, we aim to develop new applications of deep learning and neural networks for the analysis of MS data.
Stargardt’s disease is a rare inherited ocular illness that affects the Canadian population. According to Fighting Blindness Canada, 1 in 8,000 Canadians suffer from Stargardt’s, a degenerative ocular illness that ultimately leads to vision loss. Typically, patients are diagnosed with the disease by the age of 13, and most experience progressive vision loss as they get older. It is not uncommon for patients to develop complete blindness by the age of 35. Still today, despite the many clinical trials taking place, there is no cure for Stargardt’s disease.
Electric power is almost entirely transmitted through polymer insulated cables or wires in every home, factory, plant or apparatus. If the temperature of a cable increases, it would be an indication that some accidents or malfunctions such as inflow of excess electric current occur in the cable. The generated heat, indeed, degrades the polymer insulations in cable, thus, making it unsuitable and unsafe for extra service. Therefore, it would be markedly valuable if the thermally-degraded portion in a cable can be located precisely without destroying the cable.
Despite the power of gene therapy, its successful application to medicine has been diminished due to: (i) high toxicities and potentially fatal adverse effects; (ii) poor transgene expression in target cells; and (iii) extensive vector degradation. While viral vectors greatly improve efficiency, they sometimes lead to cancers due to chromosomal integration and may suffer from a lack of desired tissue selectivity. In contrast, nonviral systems have proven safer, but less efficient.