Assessment of DNA Ministring technology in cell transfection and the treatment of Colorectal Cancer (CRC)

Despite the power of gene therapy, its successful application to medicine has been diminished due to: (i) high toxicities and potentially fatal adverse effects; (ii) poor transgene expression in target cells; and (iii) extensive vector degradation. While viral vectors greatly improve efficiency, they sometimes lead to cancers due to chromosomal integration and may suffer from a lack of desired tissue selectivity. In contrast, nonviral systems have proven safer, but less efficient.

Iron battery: a safety, economic and environmentally friendly aqueous secondary battery

The past few decades have witnessed the unprecedented development of aqueous rechargeable batteries and there are many scientific groups focusing their interest on this energy technology research field. Ideal active electrode materials and plain economic considerations are the critical factors in the design of batteries. Among them, Fe//MnO2 aqueous battery is one of the best candidates because of lower cost, high safety and eco-friendliness. In addition, improved conductivity and better cycle performance can be obtained by carbon coating.

Tagging and Auto-Captioning of Histopathology Scans for Diagnosis Assistance

Digital pathology uses modern scanners to capture high-resolution images from biopsy samples. Computer algorithms, especially artificial intelligence, can help in automatic searching for similar cases in the archive of hospitals and laboratories. Displaying similar images form the past patients, that have already been diagnosed and treated, can provide useful information to the pathologist to solidify the final diagnosis. These images, however, are very large such that their processing requires smart algorithm to distinguish between relevant and irrelevant information.

Knowledge Intensive Processes Representation and Analysis: Process-Aware Work-Graphs and Predictive Approaches

Processes are important concepts in modern society since they control and standardize the interactions between businesses, consumers, governments and other organizations. However, the rise of knowledge-based industries such as financial services, healthcare, advanced manufacturing and software development have produced unstructured and knowledge-dependent processes. These Knowledge Intensive Processes (KIPs) KIPs range from partially structured to unstructured processes and require some control and standardization while guiding but not completely constraining knowledge workers’ actions.

Instituting Composite Knowledge About Living Architectural Systems

This project seeks to accumulate information on several focused research initiatives, either recently completed or currently being conducted by partners of the Living Architectural Systems (LAS) group, and provide analysis of these with respects to their potential contribution to a paradigm of “living systems” in architecture. This project is embedded in the need to transcend the communication/methodological barriers seen in traditional interdisciplinary collaborations.

Reduced-order thermo-fluid modelling of automotive interior

Recreational vehicles operating off the grid rely on battery power to maintain climate control and, by doing so, the occupants’ comfort. Extended battery usage in these vehicle can be achieved by optimizing the thermal-fluid design of the interior space through the judicious selection of insulation material, properly sized HVAC systems, window glazing, and even external paint selection. The vehicle interior represents a highly-complex thermo-fluid system in which each component affects the other.

Quantifying soil organic carbon sequestration performance of the City of Calgary Willow Biomass and Marginal Land Reclamation Demonstration Project: Assessing provincial carbon emissions offset credit opportunities

The emerging emissions trading market provides the province of Alberta an opportunity to diversify its economy and drive climate change mitigation innovation. By improving the carbon credit generating efficiency, more economic opportunities and carbon sequestration industrial applications become feasible. The City of Calgary Dewatered Biosolids Land Application - Willow Biomass and Marginal Land Reclamation Demonstration Project represents part of the first wave of large-scale biologically driven greenhouse gas mitigation innovation.

Overcoming Barriers to Sustainable Purchasing: A Case Study of Avocado Co-op

In order to meet global climate change goals, it is necessary for consumers to shift their preferences for products towards more sustainable and eco-friendly options. Two common barriers that consumers experience when purchasing green products are: 1) perceived difficulty of buying green, and 2) skepticism about the quality of green brands. Avocado Co-op is attempting to address these barriers by offering a service that delivers member-tested sustainable household products direct to the consumer.

Evaluating the Risk of Climate Change and Hydraulic Processes to Linear Infrastructure

Networks of linear Infrastructure, such as our roads and pipelines, allow us to move people, natural resources, and manufactured goods. Common practice has been to utilise historic climatic data to establish deterministic design guidelines for water course crossings. With climate change uncertainly, asset managers are in a position where they are questioning the guidelines and their current infrastructure robustness.

Uncovering Soft Information from Stock Market Conference Calls: Asset Management Perspectives

Investors, regulators, and the general public consume a wealth of textual information every day. Recent advancements in artificial intelligence make machine-reading of textual information plausible. We tackle text mining of financial conference call transcripts—calls of significant corporate events that are widely followed by investors and institutional investors. Our conference calls data include over 200,000 calls calls held by North American companies.