Investigating mycelial-plant biomass mat application to reduce early-colonizing weeds in row-crop agriculture

The intern will be investigating the use of plant crop biomass filled with fungal mycelium as means of stopping early-colonizing weeds in row crop agriculture. The crop biomass will be applied to the fields in liquid form and will solidify into a mat-like barrier. The intern will be coming up with the correct liquid formula in lab, and testing this initially in greenhouse trials. Once a suitable formula has been found, it will be produced at a larger scale and tested in fields owned by the industrial partner.

In Vacuo Glycation of Insulin

More than 2 million Canadians suffer from diabetes, a disease associated with the body’s inability to produce or effectively use insulin. The high blood sugar levels associated with diabetes can lead to serious complications such as vision loss, kidney failure, cardiovascular problems, and amputation. Therefore, diabetes patients are treated with insulin, with the aim of achieving tight control over their blood sugar levels.

Investigating the Role of Novel Fatty Acid-Binding Protein (FABP) Inhibitors as Treatments for Anxiety Disorders

Anxiety disorders and chronic stress represent major healthcare and economic burdens worldwide. Approximately 75% of Canadians who use health services for a mental illness present with anxiety disorders which may affect up to 10% of the population in terms of lifetime occurrence. Despite the large prevalence of anxiety-related disorders in Canada, there are currently a limited range of effective pharmacotherapeutic interventions.

High-Performance Sulfide-Electrolyte-Based All-Solid-State Lithium-Sulfur Batteries for Safe Electric Vehicle Applications

Lithium-sulfur (Li-S) batteries have been considered as one of the most promising candidates to meet the energy storage demand for electric vehicles due to their high theoretical energy density of 2600 Wh kg-1, low cost, natural abundance, environmental friendliness. State-of-the-art Li-S batteries, using liquid electrolytes, still have significant challenges in their safety and lifespan.

Parking Utilization Assessment Using Deep Learning

Analyzing parking behavior and usage in large open-concept retail centers enables owners and managers to better understand how their parking facility is being used. Most large, open-concept shopping centers are experiencing a parking oversupply problem. Current parking allocation is inefficient and contributes to urban sprawl, large concrete pads that trap solar heat and a waste of valuable real estate resources. Parking studies are generally conducted on foot using a combination of manual tallying or with ground level cameras used to collect imagery of ingress / egress traffic.

Learning from extreme weather: Developing the capacity of social science researchers to conduct quick response research

Quick Response Research has long allowed social, behavioural and economic science researchers to collect and integrate valuable first-response data in time-sensitive environments. This type of research is conducted during or shortly after an extreme event and allows social science researchers to collect perishable data that wouldn't be accessible otherwise. While quick response research has been used as an approach for collecting data for decades, important gaps remain in educating and training researchers in this particular form of research.

Mentorship Needs in the Ontario Manufacturing Industry

This project will identify the necessary components for a high-quality mentorship program for workers in the Ontario manufacturing industry. Through review of existing mentorship programs, interviews with mentors and mentees, and a job analysis procedure for the mentor role, this research will assess the mentoring needs of manufacturing workers. The project will produce a task-based training guide for mentors so that they can most effectively engage with mentees in order to maximize recruitment and retention.

Biphasic CO2 extraction/stripping of bioactive compounds from fermentation overlays

Recent studies have shown that cannabinoids can control chronic pain and muscle spasms as well as other diseases related to chemotherapy, AIDS and epilepsy, therefore it is very important to investigate about cannabinoids. However, it is very difficult to strip it out cheaply from the triglyceride oil while securing high purity and high concentration level; and this challenge may limit its use for medical purposes. The proposed solution to tackle the problem is to develop a liquid (CO2)-liquid or (scCO2)-liquid extraction process using unique counter-current extraction column.

Caring for the caregiver: Exploring the “lived” caregiving and self-care experiences of family caregivers of persons with scleroderma during COVID-19

Scleroderma is a rare autoimmune connective tissue disease that damages skin and internal organs. Although many Canadians with scleroderma live at home with supported care from family, seeing their loved ones struggle with reduced participation in activities of daily living caused by disease symptoms often causes caregivers emotional distress in their caregiving role.

Improved data driven sgRNA design for use in bacteria

CRISPR/Cas9 is a promising tool for genome engineering in bacteria, but it's limited by inconsistent accuracy. Though some studies have been conducted to understand why this inconsistency occurs, many important biological features have not been explored. Moreover, computer based attempts to predict accuracy have suffered from these knowledge gaps. This is due mainly to the fact that the mathematical equations that these predictions are based on, do not take these biological features into account.

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