Biomaterials for the reduction of bacterial adhesion and biofilm formation

Stents are tubes placed between the kidney and the bladder which prevent blockages which might otherwise damage the kidney. Introducing foreign material into this system allows a platform for bacteria to exist and which will potentially cause infections. These are very common. We propose modifying the surfaces of the materials used in stents to make them “non-stick” to prevent bacteria attaching and then causing infections. We can test this in the laboratory and wish to test different types of material under different conditions which mimic the clinical environment.

Advanced Analytics Initiative

Mental health issues affect a large percentage of the military population. The HERE4U Military Version will be an instant messaging smartphone application to connect military family members (adults only) who are dealing with mental health problems to a mental health counseling solution that uses the IBM Watson cognitive platform. Being able to engage with Watson in a secure, private and anonymous manner will encourage military personnel to reach out for help where they might not have in the past to obtain timely advice.

3D printing of electrochemically driven point-of-care test (POCT) device for heavy metal ions detection

This project aims to develop a fast-response, portable and mobile-readable point of care test (POCT) device. Three-dimensional (3D) printing technology is proposed to fabricate the configuration that features components and elements functioning to accommodate and integrate all principle stages of analysis, including sample pre-treatment, fluidic manipulation and signal detection.

Understanding the Impact of Fontan Circulatory Repair on Brain Blood Flow Health - Year two

Children born with an absent or ineffective right or left ventricle (single ventricle) have a low life expectancy and will undergo at least three surgical procedures ultimately leading to the Fontan Procedure (FP), which allows blood to travel directly to the lungs (bypassing the heart) to become oxygenated. Adolescent FP-patients indicate poor cardiovascular health which in turn could challenge brain blood flow, thereby affecting cognitive capacity and increasing risk of stroke. FP is a relatively new procedure and long-term effects on brain health are unknown.

Time-Dependent Effects On Vertical Shafts Used In Micro-Tunneling applications In Queenston Shale - Year two

Micro-tunneling technique is a feasible means to construct pipelines and tunnels in different types of ground including Queenston shale. However, this shale exhibits time-dependent deformation behavior, generally known as the rock swelling, which produces additional stresses on underground structures. These stresses may exceed the allowable tensile or compressive strength of concrete of the pipeline or the tunnel liner, which in-turn may result in cracks in these structures.

Exploring the Physical Education-Related Needs and Self-Efficacy of Elementary School Teachers

The objective of the proposed internship is to conduct a needs assessment to identify the challenges of teaching physical education in elementary school, and determine supports/resources to improve teachers? confidence to instruct physical education. As the GoodLife Kids Foundation supports national, provincial, and local programs that provide ongoing physical activity opportunities for kids, findings from this project will be used to inform future program planning and evaluation of prior initiatives.

Lifestyle and cognition: a large-scale approach

Online cognitive testing provides unprecedented opportunities for exploring human brain function among the general population. Cambridge Brain Sciences Inc has created an online cognitive testing platform that has attracted more than 1.5M users and has hosted more than 300 studies of cognition. I plan to leverage their unique dataset to explore the interrelationship between demographic and lifestyle factors, and cognitive performance on a massive scale.

Physiological assessment of cochlear and auditory nerve integrity in children suspected of auditory processing disorder - Year two

Nearly 2 % of school-aged children face difficulty in understanding speech in the presence of background noise. These children are often referred to audiology clinics for a central auditory processing (CAP) assessment. The purpose of the referral is to rule out an auditory processing disorder (APD). The American Speech-Language-Hearing Association recommends to include electrophysiological measures to assess the neural integrity in children sAPD. However, less than 15 % of audiologist include the electrophysiological measure in their battery of assessment.

Development and validation of analysis methods for classification of environments: classification by sound, time, and place

Hearing aids are now fully digital, advanced signal processors that monitor the type of sound coming in to the hearing aid. The sound type is automatically classified into one of several types, such as speech in a quiet place, versus telephone listening, versus in a noisy car. These sound types may require different signal processing from the hearing aid. Accordingly, the hearing aid an automatically switch into different signal processing when the sound type changes. Current methods for sound type classification do not monitor the user’s location.

Investigating the Role of Cannabis Derived Phytocannabinoid Formulations for the Development of Novel Mental Health Pharmacotherapies

Cannabinoid phytochemicals derived from the marijuana plant are increasingly being recognized for their potential in treating a wide variety of mental health conditions. For example, specific compounds found in marijuana such as THC and cannabidiol (CBD) are showing promise as pharmacological treatments for disorders including schizophrenia, anxiety, depression and PTSD. However, very little is understood regarding the underlying neurobiological and molecular mechanisms by which these treatments may produce their clinical effects.